|
|
|
| Analysis of changes of amniotic fluid and blood biochemical characteristics in patients with abnormal idiopathic amniotic fluid volume |
| YANG Chunyan WU Jiping |
| Department of Gynaecology and Obstetrics, Hebei Luzhou Hospital, Hebei Province, Luzhou 072750, China |
|
|
|
Abstract Objective To investigate the changes of amniotic fluid and blood biochemical characteristics in patients with advanced idiopathic amniotic fluid. Methods From January 2017 to June 2018, 33 pregnant women with idiopathic oligohydramnios in late pregnancy who underwent prenatal examination and delivered in Zhuozhou Hospital of Hebei Province were selected as group A, and 43 pregnant women with idiopathic hydramnios in late pregnancy were selected as group B, 52 pregnant women with normal amniotic fluid volume were selected as group C at the same period. The levels of potassium, sodium, chlorine, calcium, urea nitrogen, creatinine, carbon dioxide binding capacity, glucose, total protein and osmotic pressure in werum and amniotic fluid of three groups were observed. Results There was no significant difference in amniotic fluid potassium, chlorine, carbon dioxide binding capacity, urea nitrogen and total protein levels among the three groups (P > 0.05). The levels of amniotic fluid sodium, calcium, glucose and osmotic pressure in group A were lower than those in group B and C, and the levels of creatinine were higher than those in group B and group C, and the differences were statistically significant (P < 0.05). There was no significant difference in serum potassium, sodium, chlorine, calcium, carbon dioxide binding capacity, glucose, urea nitrogen, creatinine, total protein and osmotic pressure among the three groups (P > 0.05). Conclusion The idiopathic amniotic fluid (IAF) is not associated with serum and amniotic fluid biochemical changes in pregnant women, and there are abnormal changes in amniotic fluid biochemical components in IAF pregnant women, but the detailed mechanism remains to be further studied.
|
|
|
|
|
|
[1] 梁宏伟，张长春，陈星，等.产前超声监测羊水量不均衡双胎妊娠的临床价值研究[J].中国实验诊断学，2018，22（1）：75-77.
[2] Luo H，Xie A，Hua Y，et al. Aquaporin 1 gene deletion affects the amniotic fluid volume and composition as well as the expression of other aquaporin water channels in placenta and fetal membranes [J]. Clin Chim Acta，2018， 482：161-165.
[3] 罗静，常青，王廷洲，等.新妊娠期糖尿病诊断标准与围生期母儿结局分析[J].实用妇产科杂志，2012，28（9）：755-758.
[4] 包影，周美茜，欧荣英，等.特发性羊水减少孕妇早产情况及相关因素研究[J].中国全科医学，2014，17（22）：2616-2618.
[5] 韦稚.羊水过多产前诊断及妊娠结局分析[J].中国妇幼保健，2015，29（2）：28-30.
[6] 刘月利.联用丹参滴注液与静脉输液治疗妊娠期羊水过少的疗效分析[J].中国急救医学，2016，36（z1）：134-135.
[7] 邓青春，常青，王丹，等.足月妊娠合并羊水过少287例分娩结局[J/CD].中华妇幼临床医学杂志：电子版，2015， 11（5）：621-624.
[8] 赵慧赟.丹参对妊娠晚期特发性临界羊水过少的围产期结局的影响[J].世界中西医结合杂志，2016，11（1）：93-96.
[9] Bachhav AA，Waikar M. Low amniotic fluid index at term as a predictor of adverse perinatal outcome [J]. J Obstet Gynaecol India，2014，64（2）：120-123.
[10] 王坚红，洪鑫燊.白术散加减治疗羊水过多31例疗效观察[J].湖南中医杂志，2018，34（5）：84，95.
[11] 陈小江.晚期妊娠羊水过少与妊娠并发症的关系及对围生儿的影响[J].中国妇幼保健，2015，30（2）：187-188.
[12] Seikku L，Rahkonen L，Tikkanen M，et al. Amniotic fluid erythropoietin and neonatal outcome in pregnancies complicated by intrauterine growth restriction before 34 gestational weeks [J]. Acta Obstet Gynecol Scand，2015，94（3）：288-294.
[13] Kale E，Kale A. Amniotic fluid amino acid concentrations in fetal skeletal dysplasia[J].Clin Exp Obstet Gynecol，2014，41（3）：280-282.
[14] 蒋映雪，丁晓静，王孝君，等.原发性羊水过少与妊娠并发症的相关性及对妊娠结局的影响[J].中国妇幼保健，2018，33（1）：41-43.
[15] 高珊珊.水通道蛋白1表达水平与羊水量异常的相关性研究[J].中国现代医药杂志，2017，19（3）：24-27.
[16] 王晓静，马颖，张雅丽.妊娠晚期特发性羊水偏少孕妇羊水成分变化及对妊娠结局的影响[J].中国计划生育杂志，2018，26（6）：494-499.
[17] Anderson DF，Jonker SS，Louey S，et al. Regulation of intramembranous absorption and amniotic fluid volume by constituents in fetal sheep urine [J]. Am J Physiol Regul Integr Comp Physiol，2013，305（5）：R506-R511.
[18] 张蕊.妊娠期糖尿病患者羊水量异常成分分析及其对妊娠结局的临床应用分析[J].中国处方药，2017，32（12）：150-151.
[19] 王金凤.妊娠期糖尿病危险因素及对妊娠结局的影响[J].中国医药导报，2017，14（24）：135-138.
[20] 刘居莉，杨焕礼.妊娠期糖代谢监测预防妊娠相关并发症、胎儿不良结局价值分析[J].实用预防医学，2017，24（6）：723-725.
[21] 高珊珊.水通道蛋白1表达水平与羊水量异常的相关性研究[J].中国现代医学杂志，2017，19（3）：24-27. |
|
|
|
