罗哌卡因联合舒芬太尼在无痛分娩中的应用效果

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Abstract Objective To study the application effects of Ropivacaine combined with Sufentanil on painless childbirth. Methods From June 2016 to June 2018, 160 parturients delivered in the Second Xiangya Hospital of Central South University and Hu′nan Provincial Maternity and Child Health Care Hospital were selected, and they were divided into the Ropivacaine group and the combination group by random number table method, with 80 cases in each group. Ropivacaine group was treated by Ropivacaine for analgesia, and the combination group was treated by Sufentanil and Ropivacaine for analgesia. The analgesic effects of the two groups were compared. Prolactin (PRL) level was detected and lactation volume was compared between the two groups. Blood gas and Apgar scores of neonates were compared between the two groups. Results The analgesic effect time and complete block time of the combination group were shorter than those of Ropivacaine group, and the duration was longer than that of Ropivacaine group, the differences were statistically significant (P ＜ 0.05). The lactation initiation time of the combination group was shorter than that of Ropivacaine group, and the lactation volume and concentrations of PRL at postpartum 24 h and 48 h were higher than those of Ropivacaine group, the differences were statistically significant (P ＜ 0.05). The blood pH, artery blood oxygen partial pressure (PaO2) level of the fetus and Apgar score of neonates in the combination group were higher than those of Ropivacaine group, and artery blood partial pressure of carbon dioxide (PaCO2) level was lower than that of Ropivacaine group, the differences were statistically significant (P ＜ 0.05). The pain relief and breast distending pain relief in combination group were better than those in Ropivacaine group (P ＜ 0.05); the overall satisfaction of the combination group was higher than that of Ropivacaine group, and the total adverse reaction rate was lower than that of Ropivacaine group, the differences were statistically significant (P ＜ 0.05). Conclusion Ropivacaine combined with Sufentanil is more effective and safe for painless labor.

Key words： Ropivacaine Sufentanil Painless delivery Lactation function

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	LI Mingliang1 YIN Jianyin2 ZOU Dingquan1▲

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LI Mingliang1 YIN Jianyin2 ZOU Dingquan1▲. Application effects of Ropivacaine combined with Sufentanil in painless labor[J]. 中国医药导报, 2019, 16(1): 102-105.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I1/102

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