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| Study on the characteristics of TCM syndrome of chronic cerebral circulatory insufficiency |
| LI Nannan1 CHEN Zhigang1 MENG Fanxing1 REN Shan1 CAI Yingli1 LI Xuejun1 LIU Jialin2 |
1.The Fisrt Department of Cerebropathy, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China;
2.Department of Neurosurgery, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China |
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Abstract Objective To provide basis for TCM syndrome differentiation and treatment of chronic cerebral circulatory insufficiency through clinical observation of TCM syndrome distribution regularity and characteristics of patients suffering from chronic cerebral circulatory insufficiency. Methods All 76 patients with chronic cerebral circulatory insufficiency were the inpatients and outpatients of Dongfang Hospital of Beijing University of Chinese Medicine from January 2014 to January 2017. This paper clinically collected the TCM syndrome data about the patients with chronic cerebral circulatory insufficiency, developed the TCM syndrome observation scale, observed the TCM syndrome distribution regularity of 76 cases of patients with chronic cerebral circulatory insufficiency, input and analyzed the data, and explored the TCM syndrome distribution regularity of chronic cerebral circulatory insufficiency. Results ①In the 76 cases of patients with chronic cerebral circulatory insufficiency, the number of men was greater than women, and hypertensive disease accounted for the highest proportion in the concomitant underlying diseases, followed by dyslipidemia, diabetes, and coronary disease. ②Distribution of TCM syndrome factors: the common disease nature syndrome factors of the patients with chronic cerebral circulatory insufficiency included marrow deficient, phlegm turbidity, blood deficiency, qi deficiency and blood stasis; the common disease location syndrome factors included the brain, kidney and liver. In the complicated situation of all syndrome factors of patients with chronic cerebral circulatory insufficiency, there were only 4 cases (5.3%) with single symptom, and 65 cases (85.5%) with 2-4 symptoms. There were 29 cases (38.2%) with pure deficiency syndrome, only 1 case (1.3%) with pure excess syndrome, and 46 cases (60.5%) with the syndrome of intermingled deficiency and excess. ③A cluster analysis of 9 disease nature syndrome factors was made; when clustered into two categories, phlegm turbidity and marrow deficiency was classified as category Ⅰ, and other 7 symptoms were classified as category Ⅱ. ④The correlation between the disease nature syndrome factors of chronic cerebral circulatory insufficiency patients and the concomitant underlying diseases was analyzed respectively, and the results showed that the blood stasis showed a positive correlation with dyslipidemia (P ＜ 0.05); phlegm turbidity syndrome was positively correlated with hypertension (P ＜ 0.05). But, there was no significant correlation between other syndrome factors and underlying diseases (P ＞ 0.05). Conclusion Chronic cerebral circulatory insufficiency is a kind of disease intermingled deficiency and excess, with vital energy deficiency, blood deficiency, marrow deficiency and etc. as the root causes, and phlegm turbidity and blood stasis as the manifestations; the syndrome of phlegm turbidity and marrow deficiency in the patints suffering form chronic cerebral circulatory insufficiency complicated with atherosclerotic stenosis is more apparent. The pathogenesis of chronic cerebral circulatory insufficiency is complex, the main syndrome is intermingled deficiency and excess.
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[1] 平井俊策.平成元年度厚生省循环器病研究委托班研究报告集[R].国立循环器病，1990：80.
[2] 大友英一.脑梗塞と慢性脑循环不全症（脑动脉硬化症）[J].脑と神经，1991，43：803.
[3] 李建章.慢性脑供血不足新思维[R].中国实用神经疾病杂志，2007，10（5）：1-2.
[4] Torre JC. Alzheimers disease：how does it stars [J]. Dis J Alzheimers-Dis，2002，4：497-512.
[5] 曹淑芳.探讨慢性脑供血不足的发病原因及治疗方法[J].世界最新医学信息文摘：连续型电子期刊，2015，15（73）：99.
[6] 罗雯媛.慢性脑供血不足患者血清Hs-CRP、血脂水平的研究[J].中国实用医药，2011，6（13）：51-52.
[7] 郭富山，迟兆富.慢性脑供血不足患者的脑血流及颈动脉粥样硬化的研究[J].卒中与神经疾病杂志，2005，12（2）：92-95.
[8] 祝腊梅，陈观保.慢性脑供血不足的血流分析[J].实用全科医学，2007，5（9）：771-772.
[9] 近藤.无症状性脑血管病以及对应颈动脉病变的治疗[J].日内会杂志，2000，86（4）：781.
[10] 李建章.慢性脑供血不足新思维（2）[J].中国实用神经疾病杂志，2007，10（6）：122.
[11] 周仲英.中医内科学[M].2版.北京：中国中医药出版社，2007.
[12] 朱文峰.中医诊断学[M].北京：中国中医药出版社，2002.
[13] 国家技术监督局.中医临床诊疗术语·证候部分[S].北京：中国标准出版社，1997.
[14] 吴江.神经病学[M].北京：人民卫生出版社，2009.
[15] 李桂杰，海英.浅析眩晕中医病因病机[J].辽宁中医药大学学报，2017，19（10）：1-4.
[16] 许博涵，海英.头痛病因病机浅析[J].亚太传统医药，2016，12（9）：75-76.
[17] 贾玉，贾跃进，郑晓琳.中医对失眠认识的探讨及展望[J].中华中医药杂志，2015，30（1）：163-166.
[18] 宋新超，郭栋.从五脏角度论述耳鸣的病因病机[J].中医药导报，2017，23（14）：31-33.
[19] 李红蓉，秘红英，孙颖，等.基于脉络学说对动脉粥样硬化病因病机的认识[J].中医杂志，2017，58（16）：1359-1363，1367.
[20] 刘芳，单铃娟.高脂血症的中医辨证规律及临床证型分布探究[J].中医临床研究，2017，9（7）：47-48.
[21] 史亚楠，金香兰，赵建军，等.高血压合并腔隙性脑梗死认知障碍特点及中医证候分析[J].中华中医药杂志，2017， 32（5）：2280-2284.
[22] 赵晓霞，刘丽江，高静，等.中国人群颈动脉粥样硬化危险因素的Meta分析[J].中国老年学杂志，2016，36（19）： 4735-4739. |
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