子宫内膜异位症的中医体质分布及其发病因素的研究

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Abstract Objective To explore the distribution law of Traditional Chinese Medicine (TCM) constitution, the relationship between endometriosis and TCM constitution distribution, and the pathogenesis factors of endometriosis. Methods Based on the multi-center epidemiology, the data of the general survey and standardized collection of TCM constitution scale for patients with endometriosis and healthy women were collected. Seventy-seven cases of endometriosis patients detected by epidemiological investigations in three hospitals in Suzhou, Taizhou and Rugao in Jiangsu Province (Suzhou Yangcheng Lake Hospital, Taizhou City Integrated Traditional Chinese and Western Medicine Hospital, Rugao Chinese Medicine Hospital) from January 2016 to December 2017 were selected as study group. One hundred cases of healthy women without endometriosis were selected as control group. The database of the TCM constitution questionnaire was set up, the statistical analysis of relevant data was performed by SPSS 24.0 software. Results For the comparison analysis of different constitutions including static-blood constitution, Qi deficiency constitution, Yang deficiency constitution, Yin deficiency constitution, phlegm-dampness constitution, damp-heat constitution, Qi-stagnation constitution, moderate constitution, and special constitution, the top three constitutions in study group were Qi-stagnation constitution (39%), static-blood constitution (26%), and phlegm-dampness constitution (12%). The ratios of Qi-stagnation constitution, static-blood constitution in the study group were higher than those in the control group, the ratio of moderate constitution was lower than that in the control group, the differences were highly statistically significant (P ＜ 0.01). Combined with professional knowledge analysis, the differences in menarche age, menstrual period, menstrual blood volume, menstrual cycle, history of dysmenorrhea, abortion times, history of infertility between the two groups were highly statistically significant (P ＜ 0.01). The difference in the history of uterine surgery between the two groups was statistically significant (P ＜ 0.05). Compared with control group, the dietary factors in the study group was sweeter and greasier, the difference was statistically significant (P ＜ 0.05); the temperament factors were irritable, sentimental, and depressed, and the life factor was significant pressure increase, the differences were highly statistically significant (P ＜ 0.01). Conclusion The main disease constitution of endometriosis is Qi-stagnation constitution, the static-blood constitution and phlegm-dampness constitution are the second, while the main constitution of healthy women is moderate constitution. The formation of physical constitution is the result of multiple factors, and may be related to the menstrual period, menstrual blood volume, infertility history, dysmenorrhea history, abortion times, history of uterine surgery, eating habits and living habits.

Key words： Endometriosis Epidemiology Constitution of traditional Chinese medicine Pathogenesis factor Multi-center studies

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	CHENG Chen ZHANG Lei ZHU Li WAN Guiping▲

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CHENG Chen ZHANG Lei ZHU Li WAN Guiping▲. Research on TCM constitution distribution and pathogenesis factors of endometriosis[J]. 中国医药导报, 2018, 15(36): 117-120.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I36/117

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