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| Clinical effect of plasmakinetic resection of prostate combined with endocrine therapy on advanced prostate cancer and bladder outlet obstruction |
| WANG Guoqiang YI Faxian ZHU Xiaojun▲ CHEN Ligang |
| Department of Urology, Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Autonomous Region, Hohhot 010059, China |
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Abstract Objective To investigate the effect of plasmakinetic resection of prostate (PKRP) combined with endocrine therapy on advanced prostate cancer with bladder outlet obstruction, international prostate symptom score (IPSS) and quality of life score (QOL). Methods From January 2016 to January 2017, 60 patients with advanced prostate cancer and bladder outlet obstruction admitted to the Department of Urology, Inner Mongolia Medical University Hospital were selected as study subjects. According to the treatment, they were divided into study group and control group, with 30 cases in each group. The control group underwent simple endocrine therapy. The study group combined with PKRP treatment on the basis of the former. The clinical treatment-related indicators, IPSS score, QOL score, and survival rate were compared between the two groups. Results Maximum urinary flow rates (Qmax) and other clinical treatment-related indicators in the study group were better than those in the control group (P < 0.01). There was no significant difference in IPSS scores between the two groups before treatment (P > 0.05). IPSS scores decreased in the two groups than that before treatment (P < 0.01), and IPSS scores in the study group were lower than those in the control group after 3 months of treatment (P < 0.01). QOL scores in the study group were higher than those in the control group after 3 months of treatment (P < 0.01). Conclusion PKRP combined with endocrine therapy can effectively improve clinical symptoms and prostatic function in patients with advanced prostate cancer complicated with bladder outlet obstruction. The curative effect is definite, and it is helpful to improve the quality of life and survival rate of patients. It can be popularized and applied.
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