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Influence of common metal ions on biological activity of Acinetobacter baumannii |
YUAN Weixi LIU Haiping CAO Shunwang YU Feng CHEN Wenfang LIU Liya |
Newborn Disease Screening Center, Foshan Women and Children Hospital, Guangdong Province, Foshan 528000, China |
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Abstract Acinetobacter baumannii is the main pathogenic bacteria of hospital acquired infection. Multiple drug resistant Acinetobacter baumannii is rapidly increasing in clinical practice, which leads to a difficulty of anti-infection treatment. It is an urgent need to find better ways to effectively inhibit Acinetobacter baumannii. Metal ions are necessary to sustain the physiological process and keep virulence active in bacteria. They have been used to deal with bacterial infections before the advent of antibiotics. In this review, we focused on the influence of metal ions (Fe, Zn, Mn, Cu, etc.) on the bioactivity of Acinetobacter baumannii. We aimed to make the researchers fully understand the bacteriostasis of metal ions and supply new ways for the treatment of Acinetobacter baumannii infection.
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