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Effect of Bupi Yishen Huoxue Decoction on patients with renal anemia in the TCM symptom type of deficiency of spleen and kidney and blood stasis |
ZHANG Rongdong1 LIN Yinghua1 LIN Ying2 |
1.Department of Chinese Medicine, Ningde City Hospital Affiliated of Fujian Medical University, Fujian Province, Ningde 352100, China;
2.Department of Haematology and Rheumatology, Ningde City Hospital Affiliated of Fujian Medical University, Fujian Province, Ningde 352100, China |
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Abstract Objective To observe the effect of Bupi Yishen Huoxue Decoction on patients with renal anemia in the TCM symptom type of deficiency of spleen and kidney and blood stasis. Methods Sixty cases with renal anemia admitted to Department of Chinese Medicine, Ningde City Hospital Affiliated of FuJian Medical University from May 2017 to March 2018 were selected and they were divided into treatment group and control group, with 30 cases in each group by random number table method. The control group was given basic treatment, and the treatment group was given the Bupi Yishen Huoxue Decoction based on the treatment in the control group. The two groups were treated for 2 months. Clinical syndrome score, red blood cell (RBC), Haemoglobin (Hb), hematocrit value (HCT), blood urea nitrogen (BUN) and serum creatinine (Scr) were observed and compared between the two groups. Results After treatment, the clinical syndrome scores of the two groups were lower than those before treatment, and the differences were statistically significant (P < 0.05), the score in the treatment group was lower than that in the control group (P < 0.05). After treatment, RBC, Hb, HCT in the two groups were higher than those before treatment, the differences were significant (P < 0.05), meanwhile the levels in the treatment group were higher than those in the control group (P < 0.05). After treatment, BUN and Scr in the two groups all decreased compared to those before treatment (P < 0.05), meanwhile the levels in the treatment group were lower than those in the control group (P < 0.05). There were no obvious adverse reactions in the two groups. Conclusion Bupi Yishen Huoxue Decoction can effectively improve renal anemia and renal function, which is worth of promotion.
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