白内障超声乳化联合国产可折叠人工晶状体植入术后的安全性早期观察

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Abstract Objective To evaluate the safety of early stage in phacoemulsification combined with domestic foldable intraocular lens (IOL) implantation. Methods From October to November 2017, 14 cases of cataract patients (18 eyes) who were treated in the Department of Ophthalmology in the 211th Hospital of PLA were implanted with A1-UV one-piece foldable IOL. Intraoperative complications were recorded. The patients were followed up at 1 day, 3 days, 1 week and 2 weeks after operation. The anterior chamber depth, corneal average curvature, non-contact intraocular pressure, corneal endothelial cell density and slit lamp microscopy were measured and recorded. The result was analyzed by SPSS 20.0. Results There were no significant differences in corneal mean curvature, anterior chamber depth and non-contact intraocular pressure among different follow-up times (F = 0.991, P = 0.418; F = 3.244, P = 0.092; F = 1.445, P = 0.229). The corneal endothelial cell density was significantly decreased at 1 d, 3 d, 1 week and 2 weeks after operation (F = 19.816, P ＜ 0.001). No patient developed exudation of the anterior chamber after operation. Only mild conjunctival edema occurred 1 day after operation, and recovered to the preoperative level 3 days after operation. Mild postoperative aqueous humor cells and corneal edema occurred 1 day to 3 days after operation, and recovered to the preoperative level 1 week after operation. Mild aqueous flashes and bulbar conjunctival congestion occurred 1 day to 1 week after operation, and returned to preoperative level 2 weeks after operation. Conclusion Phacoemulsification combined with domestic foldable IOL implantation has little perturbation to the human eye and quick postoperative recovery. Domestic A1-UV foldable IOL, HS-Ⅰ injector and SI-Ⅰ import head all have good biocompatibility and safety, which is worth of clinical promotion and application.

Key words： Domestic foldable IOL Safety Biological parameters Corneal endothelial cell density Inflammatory reaction

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	WU Jingming1 LI Yunfeng1 ZHAO Zhouting1 WANG Shuainan1 SONG Wulian2

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WU Jingming1 LI Yunfeng1 ZHAO Zhouting1 WANG Shuainan1 SONG Wulian2. Observation of the early stage safety of phacoemulsification combined with domestic foldable intraocular lens implantation[J]. 中国医药导报, 2018, 15(33): 76-79.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I33/76

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