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Discussion of research status and hotspot of Zuogui Pills based on CiteSpace visualization software |
ZHANG Mingzhao1 LI Xiao2 JU Baojun1 MA Miaomiao1 ZHANG Yongtao1 LI Luyu1 YAO Junchao1 LIU Feng1 |
1.The First Clinical Medical College, Henan University of Chinese Medicine, Henan Province, Zhengzhou 450000, China; 2.Department of Andrology, the First Affiliated Hospital of Henan University of Chinese Medicine, Henan Province, Zhengzhou 450000, China |
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Abstract Objective To understand the development status and research hotspots of Zuogui Pills by CiteSpace visualization software. Methods The literatures about Zuogui Pills from January 1993 to December 2022 were searched in CNKI, VIP, Wanfang Data, Wanfang Med Oline, and China Biology Medicine Literature Service System. CiteSpace 6.2.R2 software was used to visualize the authors, institutions, keywords, and other information. Results A total of 1 050 relevant literatures were included in the study. In 2017, the number of literatures published on Zuogui Pills was the highest, with 90 articles. There were 76 authors who had published more than five literatures. The institution with the highest number of publications was Liaoning University of Traditional Chinese Medicine. There were ten keywords with frequency ≥19 in the literatures about Zuogui Pills, forming 12 natural clusters, and 25 emergent keywords. Conclusion The clinical application of Zuogui Pills involves a variety of chronic diseases, and the mechanism of action is mostly focused on molecular expression.
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[1] 黄胜男,张颖,王如然,等.左归丸治疗骨质疏松的网络药理学分析[J].中国中医基础医学杂志,2022,28(2):283- 286,290. [2] 贺晓霞,游方,钟丽君.左右归丸对多囊卵巢综合征不孕临床疗效及药理作用分析[J].辽宁中医药大学学报,2022, 24(9):52-55. [3] 毕嘉宁,李至泓,武曦蔼.基于CiteSapce知识图谱的莪术研究热点与趋势分析[J].中国医药导报,2023,20(21):146-150. [4] 陈超美,陈悦.科学发现的结构与时间属性[J].科学与管理,2014,34(3):27-32,81. [5] 许凯霞,王永辉,郭亚菲,等.左归丸含药血清对高糖负荷下ICR小鼠早期胚胎影响的蛋白组学研究[J].中华中医药杂志,2020,35(7):3598-3602. [6] 王超群,王永辉,刘涛,等.左归丸对妊娠糖尿病大鼠血清相关指标及胰腺PDX-1表达的影响[J].中国实验方剂学杂志,2020,26(19):114-119. [7] 王超群,周然,王永辉,等.左归丸母代干预对妊娠糖尿病模型大鼠子代胎鼠胰腺发育调控因子PDX-1、HNF-6的影响[J].中医杂志,2021,62(4):341-345. [8] 吴小燕,崔晓萍,范美玲,等.左归丸治疗卵巢早衰临床及实验研究进展[J].中医学报,2020,35(3):568-572. [9] 姚春鹏.黄帝内经[M].北京:中华书局,2009:19. [10] 张凤凤,崔晓萍,赵潘婷,等.崔晓萍主任医师治疗卵巢早衰经验撷英[J].西部中医药,2022,35(2):48-51. [11] 董涛,曹军华.左归丸联合骨化三醇治疗骨质疏松性股骨粗隆间骨折术后肾虚精亏型患者的临床观察[J].世界中西医结合杂志,2022,17(11):2227-2231. [12] 黄俐华,廖朝青,钟海英.左归丸加减合中药封包治疗早发性卵巢功能不全的临床效果[J].中国当代医药,2023,30(19):91-94. [13] 孙松,李海松,祝雨田,等.左归丸治疗男性不育左归丸(肾阴亏虚型)临床观察[J].中国性科学,2018,27(4):117-119. [14] 李培轮,崔云,陶方泽,等.崔云教授治疗少弱精子症对药与角药探颐[J].中华全科医学,2020,18(4):657-661. [15] 吴侠,李然,刘立萍,等.左归丸含药血清对乳腺癌MDA- MB-231细胞巨噬细胞移动抑制因子表达的影响[J].时珍国医国药,2022,33(4):804-807. [16] 吴火燕.左归丸加减辅治狼疮性肾炎肝肾阴虚证的临床观察[J].中国中医药科技,2022,29(1):117-119. [17] 邹吉轩,赵霈,宋英,等.从命门水火学说探讨左归丸、右归丸对免疫系统的调节作用[J].中国医药导报,2023, 20(8):137-140,145. [18] 赵敏,任梅荣,周艳艳,等.左归丸对肾虚仔鼠胸腺内CD4-CD8-T细胞分化的影响[J].中国实验方剂学杂志,2020,26(11):49-55. [19] 胡骏,谈钰濛,王阶.中医药对慢病预防的概况与层次划分[J].天津中医药大学学报,2021,40(4):440-444. [20] 唐皓,余娜,仇湘中,等.左归丸对去势大鼠钙转运通路相关蛋白的影响[J].中国实验方剂学杂志,2020,26(2):13-18. [21] 赵新永,李晓婷,周飞.左归丸改善自然衰老大鼠学习能力的中枢神经线粒体机制[J].中国老年学杂志,2019,39(15):3722-3725. [22] 黄展辉,魏其鹏,梁炜瑜,等.左归丸通过FNDC5/Wnt3a/ β-catenin通路治疗绝经后骨质疏松症的机制研究[J].中国骨质疏松杂志,2023,29(8):1147-1153. [23] 王彬,李霄,马凰富,等.左归丸对少弱精子症模型大鼠睾丸组织干细胞因子及其mRNA表达的影响研究[J].中国全科医学,2018,21(3):334-337. [24] Li X,Dong L,Wang J,et al. Effects of Zuogui Wan on testis structure and expression of c-Kit and Oct4 in rats with impaired spermatogenesis [J]. Pharm Biol,2020,58(1):44-50. [25] 李霄,王继升,代恒恒,等.左归丸对不育症SD大鼠Ki67蛋白及mRNA表达的影响[J].中医学报,2019,34(3):537-540. [26] 王雨琦,仇华,严如根,等.基于microRNAs差异分析和网络药理学预测左归丸化裁方治疗早发性卵巢功能不全相关机制[J].中华中医药学刊,2023,41(4):81-86, 269-273. |
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