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| Application of “internet+” based three subjects and two tracks follow-up intervention in screening of neonatal inherited metabolic diseases |
| LUO Fuyu XIE Xinxing TU Xiangwen LAI Guihua CHEN Junkun YANG Yichen |
| Newborn Disease Screening Center, Ganzhou Maternal and Child Health Hospital, Jiangxi Province, Ganzhou 341000, China |
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Abstract Objective To explore the application of “internet+” based three subjects and two tracks follow-up intervention in screening of neonatal inherited metabolic diseases(IMD). Methods A total of 4 915 IMD positive newborns from January 2020 to December 2021 in Ganzhou Maternal and Child Health Hospital of Jiangxi Province were selected as the observation group, and three subjects and two tracks follow-up intervention based on “internet +” was implemented; 5 048 newborns with positive IMD screening were selected as the control group from January 2018 to December 2019, and routine follow-up intervention was carried out. The recall situation, non-recall reasons, IMD detection situation, and recall time were compared between the two groups. The actual recalled newborns and the main guardians were included in the recall group, and the rest were included in the non-recall group, the relationship between the main guardians and the newborns, the gender of the newborns, the household registration and education background of the main guardians were compared between the recall group and the non-recall group. The contribution of telephone (including text message), WeChat group, hospital website, and hospital WeChat public number to recall in observation group were compared. Results There was significant difference in follow-up between the two groups (P＜0.05); there was no significant difference in the rate of IMD detected between the two groups (P＞0.05). There was no significant difference between the two groups in the reasons for no recall of IMD positive neonates (P＞0.05). The recall time of the observation group was shorter than that of the control group (P＜0.05). There were significant differences in household registration and education background between the recall group and the non-recall group (P＜0.05); there were no significant differences in the relationship between the main guardian and the newborn, and the newborn sex between the recalled group and the non-recalled group (P＞0.05). In the observation group, more people were recalled through ≥2 channels (phone including [text message], WeChat group, hospital website, and hospital WeChat public account). Conclusion In newborn IMD screening, the implementation of three subjects and two tracks follow-up intervention based on “internet +” can improve the recall rate, shorten the recall time, improve the efficiency of newborn IMD screening, and help early diagnosis and treatment of children. Rural household registration and low educational background are the factors affecting the recall of newborns, and multi-channel recall can be used.
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