微创经皮肾镜联合膀胱软镜治疗复杂性肾结石的效果及其对患者生活质量的影响

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Abstract Objective To analyze the effect of minimally invasive percutaneous nephrolithotomy combined with flexible cystoscopy on the treatment of complicated renal calculi and its impact on patients′ quality of life. Methods Ninety-six patients with complicated renal calculi admitted to the Department of Urology, Inner Mongolia Medical University Hospital from July 2015 to February 2018 were divided into study group (48 cases) and control group (48 cases) by random number table method. The control group was treated with minimally invasive percutaneous nephroscopy, and the study group was treated with flexible cystoscopy combined with minimally invasive percutaneous nephroscopy. The intraoperative blood loss, operation time, hospital stay, calculus rate, complications, urokinase, creatinine level and quality of life score (somatic function, emotional function, social function, cognitive function score) were compared between the two groups. Results The bleeding volume, hospitalization time, first-stage stone clearing rate, second-stage stone clearing rate, and complication rate were lower in the study group than in the control group(all P < 0.05). After treatment, the urokinase in the study group was higher than the control group and the creatinine was lower than the control group (all P < 0.01); the physical function, emotional function, social function and cognitive function score of the study group were higher than the control group (all P < 0.01). Conclusion Minimally invasive percutaneous nephrolithotomy combined with flexible cystoscopy has significant curative effect for the treatment of complicated renal calculi, which can reduce the blood loss and shorten the length of hospital stay, and it has higher rate of stone clearance, less complications. It has less effect on renal function and the patients′ quality of life is high.

Key words： Percutaneous nephrolithotomy Flexible cystoscopy Complicated renal calculi Efficacy Complications Renal function Quality of life

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	CHEN Ligang1 YI Faxian1 CHEN Lijun2 WANG Guoqiang1

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CHEN Ligang1 YI Faxian1 CHEN Lijun2 WANG Guoqiang1. Minimally invasive percutaneous nephrolithotomy combined with flexible cystoscopy for the treatment of complicated renal calculi and its impact on patients′ quality of life[J]. 中国医药导报, 2018, 15(33): 51-55.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I33/51

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