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| Predictive value of CTA combined with CTP in the treatment and rehabilitation of patients with unilateral middle cerebral artery infarction |
| CHANG Dongmei1 LI Zhiwei2▲ |
1.Department of Imaging, Suzhou Integrated Traditional and Western Medicine Hospital, Jiangsu Province, Suzhou 215101, China;
2.Department of Imaging, the Second Affiliated Hospital of Suzhou University, Jiangsu Province, Suzhou 215101, China |
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Abstract Objective To investigate the predictive value of CT angiography (CTA) combined with CT perfusion imaging (CTP) in the treatment and rehabilitation of patients with unilateral middle cerebral artery infarction. Methods A total of 89 patients with unilateral middle cerebral artery infarction who were treated in Suzhou Integrated Traditional and Western Medicine Hospital from January 2020 to October 2022 were selected, all patients were given routine treatment, follow-up to 90 days after treatment, the clinical data, CTA and CTP parameters of patients with effective (65 cases) and ineffective (24 cases) treatment, good prognosis (57 cases) and bad prognosis (32 cases) were analyzed and compared. Results There were significant differences in collateral circulation and relative cerebral volume (rCBV) between effective and ineffective patients (P＜0.05). The area under receiver operator characteristic(ROC) curves for collateral circulation (poor =1, good =0), rCBV and combined prediction of treatment failure were 0.780, 0.724, and 0.745, respectively (P＜0.05). There were significant differences in collateral circulation, rCBV, and relative mean transmit time between good and bad prognosis patients (P＜0.05). The area under ROC curve of collateral circulation, rCBV and combined prediction of poor prognosis were 0.836, 0.767 and 0.778, respectively (P＜0.05). The area under ROC curve of relative mean transmit time for predicting poor prognosis was 0.620 (P＞0.05). Conclusion CTA combined with CTP has a certain predictive value in the treatment effect and prognosis of patients with unilateral middle cerebral artery infarction, which is worth further study.
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