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| Analysis on the syndromes distribution characteristics of upper airway cough syndrome based on clinical retrospective study |
| LUO Jingshu1 MA Jianling2 SHI Liqing2 WANG Liyun2 JI Kun2 DONG Shangjuan2 FAN Yuhan1 LIU Zhilin1 |
1.The Second Clinical School of Medicine, Beijing University of Chinese Medicine, Beijing 100078, China;
2.Department of Respiratory Heat Disease, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China |
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Abstract Objective To investigate the distribution of traditional Chinese medicine syndromes of upper airway cough syndrome. Methods A total of 117 patients with upper airway cough syndrome admitted to the Department of Respiratory Heat Disease, Dongfang Hospital of Beijing University of Chinese Medicine from January 2009 to August 2023 were selected as the study objects. Their gender, age, medical history, and syndromes were statistically analyzed, and the high-frequency symptoms and commonly used Chinese medicines were systematically clustered. Results A total of 159 times were diagnosed in 117 patients, among which the syndrome of wind pathogen invading lung was the most, followed by the syndrome of dampness-heat stagnated in lung-defense phase and syndrome of phlegm-damp amassing in lung. The traditional Chinese medicine syndrome type of patients with upper airway cough syndrome was related to age (P＜0.05), but was not related to sex or common rhinitis disease type (P＞0.05). Traditional Chinese medicine syndromes were characterized by lung symptoms, wind, phlegm, dampness, and heat. Systematic clustering could be divided into three association combinations, including the syndrome of wind pathogen invading lung, the syndrome of dampness-heat stagnated in lung-defense phase, and syndrome of phlegm-damp amassing in lung. By systematic clustering, the commonly used Chinese medicine can be divided into three groups: the drugs of activating qi-flowing and dissipating phlegm for resuscitation, clearing heat and eliminating dampness, and dispelling wind and arresting cough. Conclusion The main syndromes of upper airway cough syndrome are wind evil and lung stagnation, followed by dampness-heat stagnation and phlegm-dampness accumulation of lung. The manifestations of wind, phlegm, dampness, and heat are common. Therefore, targeted treatment can be carried out in clinic.
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[1] 赖克方.慢性咳嗽[M].北京：人民卫生出版社，2019.
[2] 中华医学会呼吸病学分会哮喘学组.咳嗽的诊断与治疗指南（2021）[J].中华结核和呼吸杂志，2022，45（1）：13-46.
[3] 史利卿，马建岭，杨凯，等.慢性咳嗽中医病因病机及证候学规律的认识与探讨[J].现代中医临床，2017，24（5）：1-5.
[4] 董尚娟，史利卿，季坤，等.祛风宣肺方治疗咳嗽变异性哮喘的临床疗效观察[J].现代中医临床，2019，26（4）：6-9.
[5] 中华中医药学会肺系病分会，世界中医药学会联合会肺系病专业委员会.咳嗽中医诊疗专家共识意见（2021）[J].中医杂志，2021，62（16）：1465-1472.
[6] 李佳珊，史利卿，马建岭，等.618例慢性咳嗽患者证素特征分析[J].中华中医药杂志，2019，34（7）：3193-3196.
[7] 国家技术监督局.中华人民共和国国家标准.中医临床诊疗术语·证候部分[S].北京：中国标准出版社，2021.
[8] 李灿东.中医诊断学[M].北京：中国中医药出版社，2021.
[9] 赖克方，易芳，邱忠民，等.中国慢性咳嗽研究进展与展望[J].中华结核和呼吸杂志，2022，45（1）：1-5.
[10] 廖芯艺，黄江菊.成人上气道咳嗽综合征139例临床特征分析[J].重庆医科大学学报，2023，48（6）：696-699.
[11] 樊张杰，薛萍.基层医院上气道咳嗽综合征误诊原因分析[J].临床误诊误治，2022，35（11）：10-13.
[12] 罗景舒，史利卿，马建岭，等.上气道咳嗽综合征“鼻咳”病名及证治探析[J].江苏中医药，2022，54（11）：16-19.
[13] 马金叶，姜永红.辛菀止咳散联合穴位敷贴治疗儿童上气道咳嗽综合征痰湿恋肺证的临床研究[J].现代中西医结合杂志，2022，31（20）：2829-2833，2893.
[14] 陈妍杰，陈琦辉.祛风通窍止咳汤治疗风邪犯肺型上气道咳嗽综合征的临床疗效探析[J].中医临床研究，2022， 14（32）：79-81.
[15] Wang W，Xian M，Shi X，et al. Efficacy and safety of Sanfeng Tongqiao Diwan in the treatment of upper airway cough syndrome：a randomized，double-blind，placebo-controlled clinical study [J]. J Thorac Dis，2023，15（4）：1716-1725.
[16] 师艺航，孙增涛.从“风邪致病”论治慢性咳嗽高敏感性[J].中医杂志，2021，62（7）：638-640.
[17] 栾哲宇，杨晓，师艺航，等.基于咳嗽敏感性增高探讨风咳“风邪伏肺”的物质基础及中医治疗[J].现代中西医结合杂志，2022，31（2）：207-210，223.
[18] 郑伟彬，黄锦榕，洪春霖，等.咳嗽变异型哮喘与上气道咳嗽综合征中医体质的对比研究[J].福建中医药，2021， 52（4）：11-12，15.
[19] 王月清，孙点剑一，潘烺，等.2008—2018年北京城区某体检人群不健康饮食长期变化趋势[J].中华疾病控制杂志，2021，25（3）：289-294.
[20] Chung KF，McGarvey L，Song WJ，et al. Cough hypersensitivity and chronic cough [J]. Nat Rev Dis Primers，2022，8（1）：45.
[21] Dicpinigaitis PV，Rauf K. The influence of gender on cough reflex sensitivity [J]. Chest，1998，113（5）：1319-1321.
[22] French CT，Fletcher KE，Irwin RS. Gender differences in health-related quality of life in patients complaining of chronic cough [J]. Chest，2004，125（2）：482-488.
[23] 疏欣杨，李得民，王辛秋，等.国医大师晁恩祥“风鼽”学术思想及临证经验[J].中华中医药杂志，2022，37（8）：4492-4495.
[24] 刘智霖，史利卿，马建岭，等.难治性慢性咳嗽的“多维度病机”认识与证治浅探[J].北京中医药大学学报，2022， 45（5）：507-512.
[25] 李佳珊，史利卿，季坤，等.咳嗽并见背冷症临床辨治探讨[J].辽宁中医杂志，2021，48（2）：60-62.
[26] 王建康，钟光辉，徐程，等.张仲景论弦脉主病及脉理效应[J].中医研究，2023，36（1）：5-8. |
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