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| Research progress on the relationship between anti-neutrophil cytoplasmic antibody-associated vasculitis and infection |
| GAO Chang MA Liang GOU Shenju▲ |
| Department of Nephrology, West China Hospital of Sichuan University, Sichuan Province, Chengdu 610000, China |
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Abstract Under the current treatment strategy of glucocorticoid combined with immunosuppressants, infection has become one of the main complications and early causes of death in the treatment of anti-neutrophil cytoplasmic antibody associated vasculitis (AAV). At the same time, infection can also induce and aggravate AAV through various mechanisms, increasing the incidence and recurrence rate of AAV. In clinical practice, the clinical manifestations of active AAV and infection are similar, and it is easy to be misdiagnosed. It is necessary to distinguish infection and AAV from multiple levels and use multiple detection methods to achieve early diagnosis and treatment. With the continuous improvement of current detection methods and in-depth understanding of pathogens, it will be beneficial to further understand the close relationship between infection and AAV, and provide help for clinical differential diagnosis and treatment of the two.
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