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| Relationship between visceral fat area and cardiovascular and cerebrovascular complications in type 2 diabetes mellitus patients with normal body mass index |
| XIANG Xiaoyan1 YE Juan2▲ |
1.Department of Endocrinology, Suzhou Jiulong Hospital, School of Medicine, Shanghai Jiao Tong University, Jiangsu Province, Suzhou 215028, China;
2.Department of Medical Imaging, Suzhou Jiulong Hospital, School of Medicine, Shanghai Jiao Tong University, Jiangsu Province, Suzhou 215028, China |
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Abstract Objective To investigate the relationship between visceral fat area and cardiovascular and cerebrovascular complications in type 2 diabetes mellitus patients with normal body mass index (BMI). Methods From January 2018 to May 2021, 44 patients with type 2 diabetes mellitus and cardiovascular and cerebrovascular complications （24 cases of combined coronary heart disease and 20 cases of cerebral infarction）with normal BMI who were treated in Suzhou Jiulong Hospital, School of Medicine, Shanghai Jiao Tong University were selected as the observation group, and 132 patients with simple type 2 diabetes mellitus with normal BMI were selected as the control group. The differences in visceral fat area, fasting glucose (FPG), fasting insulin (FINS), insulin resistance index (HOMA-IR), etc. between the two groups were compared, and the receiver operating characteristic (ROC) curve was drawn to analyze the diagnostic value of visceral fat area for type 2 diabetes mellitus patients with normal BMI complicated with cardiovascular and cerebrovascular diseases. Results There were significant differences in diabetes course, smoking proportion, visceral fat area, FPG, FINS and HOMA-IR between the two groups (P＜0.05). Logistic regression analysis showed that the course of diabetes (OR=2.440, 95%CI:1.483-4.014), smoking [OR=3.013, 95% CI:1.730-5.247), visceral fat area [OR=2.250, 95%CI:1.459-3.470) were the influencing factors of patients with cardiovascular and cerebrovascular complications (P＜0.05), the area under the ROC curve of this equation was 0.820 (95%CI:0.746-0.894, P＜0.05), sensitivity and specificity were 75.00% and 78.00%, respectively. Conclusion The visceral fat area of type 2 diabetes mellitus patients with normal BMI and cardiovascular and cerebrovascular complications increases, which has certain diagnostic value for the disease.
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