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Research progress of molecular spectroscopy in the detection of Chlorpromazine |
ZHANG Huifeng SONG Zhifeng |
Quality Supervision, Inspection, and Testing Center of Agricultural Products and Processed Products of Ministry of Agriculture and Rural Affairs (Changchun), Institute of Agricultural Quality Standard and Testing Technology, Jilin Academy of Agricultural Sciences, Jilin Province, Changchun 130033, China |
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Abstract Chlorpromazine is widely used psychoactive substance in clinical practice, which has become a hot topic of clinical attention due to its inhibitory effect on virus and its abuse. Molecular spectroscopy is not only an important means for the construction of detection system and the analysis of reaction mechanism, but also the basis for the development of new detection technologies. Based on the phenomena of absorption, emission, and scattering generated by molecular motion, this paper reviews the application progress of ultraviolet visible spectroph-otometer, molecular fluorescence, chemiluminescence, surface enhanced Raman scattering, resonance Rayleigh scattering, and other spectral technologies in Chlorpromazine analysis from the aspects of determination principle and conditions, and discusses and prospects the application prospect of molecular spectroscopy in chlorpromazine related research. In order to provide reference for the detection, pharmacology, toxicology, and risk assessment of Chlorpromazine.
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