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| Report of two cases of macrocy-sticmicrocolon-intestinal hypoperistalsis syndrome and literature review |
| YANG Wenqiang1 ZHANG Ning2 CHENG Lingxi2 LUO Yanmei2 YANG Xinghai2 |
1.School of Medicine, Wuhan University of Science and Technology, Hubei Province, Wuhan 430065, China;
2.Department of Pediatric Surgery, Maternal and Child Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province, Wuhan 430070, China |
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Abstract Megacystismicrocolon-intestinal hypoperistalsis syndrome (MMIHS) is a rare pseudoileus syndrome, the clinical manifestations are large bladder, small colons, and gastrointestinal motility disorders caused by non-mechanical obstruction, which can occur in the neonatal period. This paper reports two cases of MMIHS, one case was a one day-old newborn. Abdominal distension was the main clinical manifestation, and the diagnosis of MMIHS was confirmed by imaging and histological examination. Although the patient received gastrostomy, anti-infection, intravenous nutrition, and other treatment, but did not achieve a good effect, and eventually died due to multiple organ failure. The other case was diagnosed as MMIHS by prenatal MRI and was recommended to terminate pregnancy, which was confirmed by pathological examination after induction of labor. In this paper, the clinical manifestations, diagnosis, and treatment of the patients were reported, and the relevant literatures were reviewed in order to improve the understanding of the disease and reduce misdiagnosis or missed diagnosis.
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