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| A randomized controlled study of subcutaneous Nitroglycerin injection for radial artery catheterization in the snuff box area |
| LIU Peizhong1 LIANG Yupeng1▲ LI Wenjin1 WEI Chao1 LI Chuangpeng1 YANG Ping1 PENG Se1 GUO Yipeng2 |
1.Department of Cardiovascular Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine Zhuhai Hospital, Guangdong Province, Zhuhai 519000, China;
2.Faculty of Chinese Medicine Science, Guangxi University of Chinese Medicine, Guangxi Zhuang Autonomous Region, Nanning 530028, China |
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Abstract Objective To investigate the clinical value of subcutaneous Nitroglycerin injection in radial artery catheterization through the snuff box area. Methods A total of 200 patients with percutaneous coronary angiography in Zhuhai Hospital Guangdong Provincial Hospital of Traditional Chinese Medicine Zhuhai Hospital from July 2021 to February 2023 were selected, they were randomly divided into control group (102 cases) and study group (103 cases) by digital parity method. The control group was injected a mixture of subcutaneously with Lidocaine and saline solution at the puncture site, while the study group was injected a mixture of Lidocaine and Nitroglycerin subcutaneously at the puncture site. The length and short diameter of the artery lumen, the successful proportion of first needle puncture, the number of puncture needles, the successful time of catheterization, the success rate of catheterization, the incidence of vasospasm, the proportion of sheath tube types, the incidence of hematoma, and the incidence of radial artery occlusion 24 h after surgery. Results There were no significant differences in mean arterial pressure difference, heart rate difference between two groups after administration (P＞0.05). The incidence of vasospasm in the study group was lower than that in the control group, the success rate of catheterization in the study group was higher than that in the control group, the difference was statistically significant (P＜0.05). After local anesthesia, the length and short diameter of the radial artery lumen in the snuff bottle area of the study group were significantly longer than those before local anesthesia, the differences were statistically significant (P＜0.05), while the difference was not statistically significant in the control group (P＞0.05). After local anesthesia, the length of the radial artery lumen in the snuff bottle area of the study group was longer than that of the control group, the difference was statistically significant (P＜0.05). There were no significant differences in the proportion of sheath type, successful proportion of first needle puncture, number of puncture needles, successful catheterization time, intraoperative heparin dosage, and pressure hemostasis time among groups (P＞0.05). There was no significant difference in the incidence of postoperative vasospasm, operative hematoma, forearm hematoma, near radial occlusion, far radial occlusion, dissection, and ultrasonic lumen diameter between the two groups (P＞0.05). Conclusion Subcutaneous injection of Nitroglycerin before radial artery catheterization through the snuff pot area can dilate the artery, reduce the occurrence of radial artery spasm before catheterization, improve the success rate of catheterization, and have good safety, which is worthy of clinical popularization.
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