|
|
Application effect of early warning model based on BISAP-HDL combined with cluster nursing in patients with acute pancreatitis |
SHEN Guanhong1 YANG Yang2▲ XU Hanli3 |
1.Department of Thoracic Surgery, the 904th Hospital of Joint Support Force of Chinese People’s Liberation Army, Jiangsu Province, Wuxi 214151, China; 2.Department of General Surgery, the 904th Hospital of Joint Support Force of the Chinese People’s Liberation Army, Jiangsu Province, Wuxi 214151, China; 3.Department of Cardiology, the 904th Hospital of Support Force of the Chinese People’s Liberation Army, Jiangsu Province, Wuxi 214151, China |
|
|
Abstract Objective To explore the application effect of early warning model based on bedside index for severity in acute pancreatitis-high density lipoprotein (BISAP-HDL) combined with cluster nursing in patients with acute pancreatitis(AP). Methods Eighty AP patients treated in the 904th Hospital of Joint Support Force of Chinese People’s Liberation Army from February 2021 to February 2022 were prospectively selected as the study objects, they were divided into control group (n=42) and observation group (n=38) by random number table method. The control group was given cluster nursing, and the observation group was given early warning model nursing based on BISAP-HDL combined wite cluster. Acute physiological and chronic health scores Ⅱ(APACHEⅡ), BISAP-HDL scores, length of hospital stay, abdominal pain relief time, amylase recovery time, immune function and inflammatory factor levels before and after treatment were compared between the two groups 24 h before treatment and one week after treatment, and the mortality rate at 28 days after admission was compared between the two groups. Results One week after treatment, the scores of APACHEⅡ and BISAP-HDL in both groups were lower than those before 24 h treatment, and the observation group was lower than the control group (P<0.05). The hospitalization time, abdominal pain relief time and hematuric amylase recovery time in observation group were shorter than those in control group (P<0.05). After treatment, CD4+ in both groups was higher than those before treatment, and the observation group was higher than that of the control group (P<0.05). CD8+, immunoglobulin G, interleukin-6, tumor necrosis factor-α, and C-reactive protein in two groups were lower than those before treatment, and observation group was lower than control group (P<0.05). The fatality rate at 28 days after admission in the observation group and the control group was 7.89% (3/38) and 16.67% (7/42), respectively, with no significant difference (P>0.05). Conclusion Early warning model based on BISAP-HDL combined with cluster nursing is beneficial to the recovery of AP patients, improving their immune function and inflammatory factor levels.
|
|
|
|
|
[1] 孙备,李冠群.急性胰腺炎临床研究进展与展望[J].中国实用外科杂志,2020,40(2):171-175. [2] 沈珊梦,张依妮,王丹妮.全程护理联合家属陪伴对急性胰腺炎患者临床观察和预后的影响[J].广东医学,2020, 41(20):2132-2136. [3] Tanaka A,Zhou Y,Ogawa M,et al. STAT1 as a potential prognosis marker for poor outcomes of early stage colorectal cancer with microsatellite instability [J]. PLoS One,2020,15 (4):e0229252. [4] 中华医学会外科学分会胰腺外科学组,中国急性胰腺炎诊治指南(2021)[J].浙江实用医学,2021,26(6):511-575. [5] Teasdale G,Jennett B. Assessment of coma and impaired con- sciousness. A practical scale [J]. Lancet,1974,2(7872):81- 84. [6] 张艳,张绣姜,孟哲,等.血清TG水平和BISAP评分对重症急性胰腺炎患者感染性胰腺坏死的预测价值[J].山东医药,2022,62(1):52-55. [7] 时毓雯,吴琼,王玉刚,等.急性胰腺炎:预后标志物的研究进展[J].胃肠病学和肝病学杂志,2022,31(3):349-353. DOI:10.3969/j.issn.1006-5709.2022.03.025. [8] Khanna S,Palackdharry S,Roof L,et al. Determining the molecular landscape and impact on prognosis in HPV-associated head and neck cancer [J]. Cancers Head Neck,2020, 5(1):11. [9] Lelièvre P,Sancey L,Coll JL,et al. Iron Dysregulation in Human Cancer:Altered Metabolism,Biomarkers for Diagnosis,Prognosis,Monitoring and Rationale for Therapy [J]. Cancers,2020,12(12):3524. [10] 顾竹君,李捷壮,黄懿波.加速康复外科理念对急性胰腺炎患者炎症因子及肠道功能恢复的影响[J].中国医药科学,2021,11(7):207-210. [11] 张媛,关静,蒋锐,等.左旋紫草素对大鼠重症急性胰腺炎并发急性心肌损伤的保护作用研究[J].成都医学院学报,2021,16(5):557-560. [12] 徐劲,彭燕,唐川康.早期中性粒细胞与淋巴细胞比值联合载脂蛋白A-Ⅰ对急性胰腺炎严重程度的预测价值[J].临床肝胆病杂志,2021,37(3):660-665. [13] 刘见欢,陈婉婵,尹爱平,等.急性胰腺炎患者血清脂肪酶,血清淀粉样蛋白A,转铁蛋白水平变化及其与病情严重程度的相关性[J].中国当代医药,2022,29(2):130-132. [14] 郑吉敏,张建,高俊茶.BISAP评分联合C反应蛋白对急性胰腺炎严重程度的早期评估价值[J].中华医学杂志,2015,95(12):925-928. [15] 田军,徐萍.胱天蛋白酶募集域蛋白9在大鼠急性胰腺炎相关肺损伤中的作用及其机制[J].中华实验外科杂志,2022,39(1):35-40. [16] 黄静雯,徐桂芳,倪牧含,等.内镜腔内引流术治疗急性胰腺炎合并胰腺包裹性坏死或假性囊肿的长期疗效分析[J]. 中华消化内镜杂志,2022,39(2):128-132. [17] 陈美颖,陈木欣,王明欣,等.重症急性胰腺炎患者并发急性肾损伤危险因素的Meta分析[J].中国全科医学,2022,25(30):3834-3842. [18] 廖国豪,程斌,余红雨,等.中性粒细胞与淋巴细胞比值和血小板计数与淋巴细胞比值与胆源性急性胰腺炎严重程度及并发肝损伤的相关性研究[J].中国全科医学,2022,25(12):1449-1454. [19] 林钰洁,肖继红,刘鑫,等.坏死性凋亡在急性胰腺炎作用机制中的研究进展[J].中华危重病急救医学,2022, 34(3):329-332. [20] 陈三洋,宋耀东,崔宗朝,等.过表达TRIM27通过抑制NF-κB/MAPK信号通路减轻小鼠重症急性胰腺炎[J].中华急诊医学杂志,2022,31(9):1186-1192. [21] 李勤,刘超男,凌莉琴,等.凝血相关的实验室指标对急性胰腺炎患者的病情和预后有较高预测价值[J].南方医科大学学报,2022,42(7):1006-1012. [22] 韦琴,申鼎成,宁彩虹,等.危重型急性胰腺炎进一步分型价值研究[J].中国实用外科杂志,2022,42(2):167- 171. [23] 杜慧清,杜慧静,耿栋栋.miR-375调控PIAS1对急性胰腺炎腺泡细胞增殖,凋亡的影响[J].中国老年学杂志,2022,42(1):202-207. [24] 李瑞,张宇艳,李若畅,等.急性胰腺炎严重程度预测模型的建立与验证[J].中华消化杂志,2021,41(8):554- 560. [25] Hosoda T,Katayama M. Epidemiology and prognosis of ommaya reservoir-related bacterial meningitis in adult patients with leptomeningeal metastases from solid tumors:A 10-year retrospective single-center study in Japan [J]. J Infect Chemother,2021,27(3):486-491. [26] 王欣然,钟丽霞,张晓雪.急性胰腺炎患者胰腺外分泌功能不全识别及护理的研究进展[J].中华护理杂志,2020, 55(12):1871-1875. [27] 曹利军,付路,黎命娟,等.急性胰腺炎严重程度临床指数联合腹内压测定对胰腺炎严重程度及预后的预测价值[J].中华普通外科杂志,2022,37(2):118-121. [28] 陈莹,李越.BISAP评分联合血清TG,MAP1-LC3检测对急性重症胰腺炎患者病情及预后的评估价值[J].山东医药,2020,60(1):21-24. |
|
|
|