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| Effect of Yunnan Hongyao Capsules in the treatment of patients with retinal vein obstruction of qi stagnation and blood stasis and Qi-Yin deficiency syndrome |
| SHI Yinjuan1 WU Huqiang2 LI Yuanbi2 LI Wenjun2 LI Yueming2 XIA Zemei2▲ |
1.Department of Ophthalmology, Anning First People’s Hospital, Yunnan Province, Anning 650300, China;
2.Department of Ophthalmology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Yunnan Province, Kunming 650000, China |
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Abstract Objective To explore the effect of Yunnan Hongyao Capsules in treating patients with retinal vein obstruction of Qi stagnation and blood stasis and Qi-Yin deficiency syndrome. Methods Fifty hospitalized patients with retinal vein occlusion and fundus hemorrhage admitted to the Department of Ophthalmology, Yunnan Provincial Hospital of Traditional Chinese Medicine from June 2019 to May 2020 were divided into control group and experimental group according to random number table method, with 25 cases in each group. The control group and the experimental group were treated with Calcium Hydroxybenzene Sulfonate and Yunnan Hongyao Capsules respectively. The visual acuity level, fundus condition, macular edema, overall treatment effect, and coagulation function indexes were compared between the two groups. Results After treatment, the visual acuity level of the two groups were higher than those before treatment, while that of the experimental group was higher than that of the control group, and the differences were statistically significant (P＜0.05). The improvement of fundus in experimental group was better than that in control group, and the difference was statistically significant (P＜0.05). After treatment, macular edema in the two groups were lower than before treatment, while that of the experimental group was lower than that of the control group, and the differences were statistically significant (P＜0.05). The overall treatment effect of the experimental group was better than that of the control group, and the difference was statistically significant (P＜0.05). After treatment, the thrombin time, activated partial thrombin time, and prothrombin time of the two groups were shorter than before treatment, and the fibrinogen time was lower than before treatment, while the thrombin time, activated partial thrombin time, and prothrombin time of the experimental group were longer than those of the control group, and the fibrinogen time of the experimental group was higher than that of the control group, and the differences were statistically significant (P＜0.05). Conclusion In the treatment of fundus hemorrhage with retinal vein obstruction, Yunnan Hongyao Capsules combined with Calcium Hydroxybenzene Sulfonate can effectively improve the visual acuity level, fundus condition, and coagulation function index, thereby reducing the thickness of macular fovea and improving the therapeutic effect.
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