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| Study on the medication rules of Categorized Collection of Medical Formulas in treatment of stomach stuffiness disease |
| TANG Yi WANG Baixin LI Min ZHU Li |
| Department of Spleen and Stomach Diseases, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China |
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Abstract Objective To study and summarize the medication rules of the prescription included in Categorized Collection of Medical Formulas for the treatment of stomach stuffiness disease. Methods Excel 2016, IBM SPSS Modeler 18.0, and IBM SPSS Statistics 25 were used to make statistics on the frequency of drugs contained in the prescriptions for treating stomach stuffiness disease in the “fivezang men”, “zhuqi men”, “piwei men”, and “zhangman men” in the Categorized Collection of Medical Formulas. The efficacy, four natures, five flavours, distribution of channel tropism and use proportion of aromatic drugs were observed. Apriori association rule analysis and network analysis were performed for all drugs, and systematic cluster analysis was performed for high-frequency drugs. Results Categorized Collection of Medical Formulas was screened 426 prescriptions for the diagnosis of stomach stuffiness disease, involving 207 kinds of drugs, mainly to regulating qi-flowing drugs and tonifying deficiency drugs to treat stomach stuffiness disease, of which regulating qi-flowing drugs mainly to Citri Reticulatae Pericarpium, Aucklandiae Radix, tonifying deficiency drugs mainly to Glycyrrhizae Radix Et Rhizoma, Ginseng Radix Et Rhizoma, Atractylodis Macrocephalae Rhizoma. The four nature and five flavour of drugs were mainly pungent, bitter, and warm, and the channel tropism of drugs were mainly spleen, stomach, lung, and kidney channels. Aromatic drugs accounted for 32.90% of the total drug frequency. A total of 15 binomial association rules were obtained, and high-frequency drugs could be grouped into nine categories. Conclusion In Categorized Collection of Medical Formulas, the method of regulating qi and tonifying deficiency is the basic principle of treating stomach stuffiness disease, and on this basis, the method of warming, eliminating phlegm (dampness) and eliminating food is used.
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