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| Effect of Angelica Buxue Decoction on patients with early lung cancer after resection |
| SHI Shengyu1 WANG Xuwen1 ZHAO Liangwei2 DU Yanqing1 JIANG Ming3 LIU Chongbin4 |
1.Department of General Surgery, Huzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University, Zhejiang Province, Huzhou 313000, China;
2.Department of Urology, Huzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University, Zhejiang Province, Huzhou 313000, China;
3.Department of Anesthesiology, Huzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University, Zhejiang Province, Huzhou 313000, China;
4.Medical College, Huzhou Teachers College, Zhejiang Province, Huzhou 313000, China |
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Abstract Objective To investigate the effect of Danggui Buxue Decoction on patients with early lung cancer after resection. Methods By random number table method, a total of 94 patients with early lung cancer admitted to Huzhou Hospital of Traditional Chinese Medicine in Zhejiang Province from February 2021 to September 2022 were divided into experimental group and control group, with 47 cases in each group. All patients underwent partial pulmonary resection. The control group was given Pemetrexed combined with Cisplatin, and the experimental group was given angelica blood-supplementing decoction. The clinical efficacy, traditional Chinese medicine syndrome score, tumor marker level, and treatment safety of the two groups were compared. Results The clinical effect of the experimental group was better than that of the control group, and the difference was statistically significant (P＜0.05). After treatment, the scores of coughing hemoptysis, chest depression, fatigue, and tongue purpleness in the two groups were lower than before treatment, while those of the experimental group were lower than those of the control group, the differences were statistically significant (P＜0.05). After treatment, the levels of phosphatidylkinol 3-kinase, protein kinase, soluble tumor necrosis factor receptor in the two groups were lower than before treatment, while those of the experimental group were lower than those of the control group, and the differences were statistically significant (P＜0.05). There was no significant difference in the total incidence of adverse reactions (P＞0.05). Conclusion Angelica Buxue Decoction has good therapeutic effect on patients with early lung cancer after resection, can improve the symptoms of patients and reduce the level of tumor markers.
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