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| Effect of electroacupuncture on metabolic state of patients with metabolic syndrome caused by atypical antipsychotics agents |
| ZHANG Peng ZHU Xianghua HE Qing |
| Department of Traditional Chinese Medicine, Xuzhou Oriental People′s Hospital, Jiangsu Province, Xuzhou 221004, China |
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Abstract Objective To explore the effect of electroacupuncture on metabolic state of patients with metabolic syndrome caused by atypical antipsychotics agents. Methods Ninety-two patients with metabolic syndrome caused by atypical antipsychotics agents in Xuzhou Oriental People′s Hospital in Jiangsu Province from January 2016 to December 2017 were selected as research subjects. They were randomly divided into study group (n = 46) and control group (n = 46) according to envelope method. On the basis of atypical antipsychotic agents, both groups were treated with diet control and exercise intervention. In addition, the study group was treated with electroacupuncture, 30 minutes each time, once a day, every 5 d treatment was followed by 2 d interval, 1 month was as a course, total for 3 courses. The changes of blood glucose, blood lipids, blood pressure, liver and kidney function, body mass index and waist circumference before and after treatment were detected and compared between the two groups. During treatment, the side effect of the two groups was compared by the treatment emergent symptom scale (TESS). Results Compared with before treatment, blood glucose, blood lipids, blood pressure, body mass index, waist circumference and other indicators were improved after treatment in the study group (P < 0.05). Compared with the control group, blood glucose, blood lipid, blood pressure, body mass index, waist circumference and other indicators were improved in the study group after treatment, the differences were statistically significant (P ＜ 0.05). There was no significant difference in liver and kidney function between the two groups before and after treatment (P ＞ 0.05). There was no significant difference in TESS score between the two groups (P ＞ 0.05). Conclusion On the basis of diet control and exercise intervention, electroacupuncture can effectively improve the metabolic state of patients with metabolic syndrome caused by atypical antipsychotics agents. It has good safety and is worthy of clinical trial.
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