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| Value of color Doppler ultrasound features in differential diagnosis of br-east asymptomatic inflammatory changes and invasive ductal carcinoma |
| QI Lin1 ZHANG Huanhuan1 SHEN Zifang1▲ YANG Rui2 |
1.Department of Functional, Wuxi Maternal and Child Health Hospital Affiliated to Nanjing Medical University, Jiangsu Province, Wuxi 214000, China; 2.Institute of Prenatal and Genetic Medicine, Wuxi Maternal and Child Health Hospital Affiliated to Nanjing Medical University, Jiangsu Province, Wuxi 214000, China
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Abstract Objective To analyze the value of color Doppler ultrasound features in differential diagnosis of breast asymptomatic inflammatory changes and invasive ductal carcinoma. Methods Patients with asymptomatic inflammatory changes diagnosed and confirmed by pathology who admitted to Wuxi Maternal and Child Health Hospital Affiliated to Nanjing Medical University from January 2019 to December 2021 were selected as inflammation group (41 cases), and invasive ductal carcinoma patients as tumor group (91 cases). The size, shape, growth orientation, echo, and calcification of the lesions were investigated by color Doppler ultrasonography; Adler semi-quantitative method was used to evaluate the blood flow signal, and the blood flow resistance index (RI) and peak systolic velocity (PSV) were measured; the model equation of color Doppler ultrasonography in diagnosis of invasive ductal carcinoma was analyzed by logistic regression; the receiver operation characteristic curve was drew, the diagnostic value of color Doppler ultrasonography in invasive ductal carcinoma was evaluated. Results There were no significant differences in lesion shape, edge state, and internal echo between two groups (P＞0.05); there were significant differences in growth orientation, posterior echo, calcification, Adler grade, RI, and PSV between two groups (P＜0.05). The equation for diagnosing invasive ductal carcinoma with color Doppler ultrasound features was Log (P) = 0.654× growth orientation +0.619× posterior echo +0.702× calcification +0.718×Adler grade +0.707×RI+0.668×PSV. The area under the curve of the color Doppler ultrasound characteristic model for diagnosing invasive ductal carcinoma were 0.894 (95%CI: 0.848-0.941), sensitivity was 89.10%, and specificity was 76.80%. Conclusion The logistic regression model based on color Doppler ultrasound features has a high value in the differential diagnosis of breast asymptomatic inflammatory changes and invasive ductal carcinoma.
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