腹腔镜直肠癌根治术后低位前切除综合征发生风险分析

doi:10.20047/j.issn1673-7210.2023.26.28

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Abstract Objective To analyze the risk of low anterior resection syndrome (LARS) after laparoscopic radical resection of rectal cancer. Methods A total of 80 patients with rectal cancer who underwent laparoscopic radical resection of rectal cancer in Huangshan People’s Hospital Anhui Province from June 2017 to January 2020 and were followed up for 24 months were selected as the study subjects. Patients were divided into LARS group and non-LARS group according to whether or not occurred LARS after surgery. Clinical data of patients were collected to analyze the related factors that may affect the occurrence of LARS in patients after laparoscopic radical resection of rectal cancer, and the risk factors were identified by logistic regression analysis. Results A total of 80 patients followed up for 24 months, 49 (61.25%) of the patients with LARS were the LARS group, and 31 (38.75%) of the patients without LARS were the non-LARS group. Univariate analysis showed that the anastomotic distance from stamo to anus in the LARS group was shorter than the non-LARS group (P＜0.05), and the proportion of body mass index (BMI)＞25 kg/cm2 in the LARS group was higher than that in the non-LARS group (P＜0.05). Logistic regression analysis showed that BMI＞25 kg/cm2 (OR=2.385, 95%CI: 1.875, 2.895), anastomotic distance from the anus (OR=0.321, 95%CI:-0.381, 1.023) were risk factors for LARS in rectal cancer patients undergoing laparoscopic radical resection for rectal cancer (P＜0.05). Conclusion BMI and the anastomotic distance from stoma to anus are important influencing factors for LARS in patients with rectal cancer after operation, and the risk of LARS is high. Identifying risk factors is helpful for clinical selection of scientific surgical methods and reduction of LARS incidence.

Key words： Laparoscopy Rectal cancer Radical surgery Low anterior resection syndrome Risk factors

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	HUANG Junjie1 ZHENG Weiqing1 WANG Zhaohui2 REN Jian1▲

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HUANG Junjie1 ZHENG Weiqing1 WANG Zhaohui2 REN Jian1▲. Risk analysis of low anterior resection syndrome after laparoscopic radical resection of rectal cancer[J]. 中国医药导报, 2023, 20(26): 130-133.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.26.28 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I26/130

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