剪切波弹性成像技术在慢性阻塞性肺疾病患者病情严重程度中的诊断价值

doi:10.20047/j.issn1673-7210.2023.22.31

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Abstract Objective To investigate the diagnostic value of shear wave elastography (SWE) technique in the severity of patients with chronic obstructive pulmonary disease (COPD). Methods A total of 73 patients with stable COPD admitted to Department of Respiratory, Affiliated Hospital of Yunnan University from March to October 2022 were selected as the study objects. According to the results of lung function examination, they were divided into mild-moderate group (44 cases) and severe group (29 cases). Intercostal muscle thickness at end inspiration (ICMTei), diaphragmatic thickness at end inspiration (DTei), shear wave elastography of intercostal muscle (ICMswe), and shear wave elastography of diaphragm (Dswe) were compared between two groups; the influencing factors of disease severity in COPD patients were analyzed by logistic regression; the diagnostic efficacy of ultrasonic parameters on COPD disease severity was analyzed by receiver operating characteristic curve; and Pearson correlation coefficient was used to analyze the correlation between ultrasonic parameters and clinical characteristics of COPD patients. Results The six-minute walk test (6MWT) in severe group was shorter than that in mild-moderate group, and the difference was statistically significant (P＜0.05). ICMswe and Dswe in severe group were higher than those in mild-moderate group, and the difference was statistically significant (P＜0.05); there were no significant differences in ICMTei and DTei between two groups (P＞0.05). Dswe was a risk factor for severe COPD (OR=1.309, P＜0.05). The cut-off value of Dswe in the diagnosis of severe COPD was 18.75 kPa, the area under the curve was 0.859 (95%CI: 0.772-0.945), the sensitivity was 89.7%, the specificity was 75.0%. Dswe was negatively correlated with 6MWT (r=-0.458, P＜0.01). Conclusion SWE technique can quantitatively assess respiratory muscle hardness and has diagnostic value in the severity of COPD patients.

Key words： Chronic obstructive pulmonary disease Shear wave elastography; Diaphragm Intercostal muscle

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	LI Rujin CHEN Jianfu YANG Hanning SUN Yue LU Yongping

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LI Rujin CHEN Jianfu YANG Hanning SUN Yue LU Yongping. Diagnostic value of shear wave elastography technique in the severity of patients with chronic obstructive pulmonary disease[J]. 中国医药导报, 2023, 20(22): 141-144,149.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.22.31 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I22/141

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