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| Research progress of pulmonary hypertension in risk stratification of acute pulmonary embolism |
| WU Nan1 XING Xiqian2 YANG Jiao1▲ |
1.Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Kunming Medical University, Yunnan Province, Kunming 650032, China; 2.Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Yunnan University, Yunnan Province, Kunming 650021, China
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Abstract Acute pulmonary embolism (APE) has a high mortality rate in China. Early correct risk stratification of APE patients can improve the prognosis of patients. The traditional risk stratification is based on the patient’s hemodynamics as a reference. Currently, pulmonary arterial pressure in APE patients is a hot topic of clinical attention, and the incidence of clinical adverse events in APE patients with pulmonary arterial hypertension is generally increased. At the same time, some biomarkers, such as brain natriuretic peptide, D-dimer, cardiac troponin I are related to pulmonary artery pressure. These indicators also have reference value for risk stratification and prognosis of APE patients. This article reviews the pathophysiology and pulmonary artery pressure of APE, as well as the combination of the three biomarkers mentioned above, in the risk stratification and prognosis of APE patients, providing new ideas for APE risk stratification.
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