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| Comparative study of imaging and pathological manifesations of inflammatory myofibroblastic tumor |
| LIAO Jiang CHEN Jiayou ZHENG Xiang FANG Yanhong XU Shugui RAO Yanying CHEN Ying▲ |
| Depatment of Diagnostic Radiology, Fujian Province Tumor Hospital, Fujian Province, Fuzhou 350014, China |
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Abstract Objective To investigate the image features combined with pathological changes of inflammatory myofiroblastic tumor (IMT), in order to improve diagnostic level. Methods From May 2008 to December 2017, in Fujian Province Tumor Hospital, the CT and MRI findings of 11 patients with IMT confirmed by histopathology on surgically resected specimen were retrospectively. The location, size, shape, density or signal, and contrast enhancement of these tumors were analyzed. Results In 11 cases of IMT, 3 cases occurred in lung, 2 cases oceurred in stomach, abdominal cavity, abdominal wall, mesentery, bladder, ureter and leg soft tissue was 1 case respectively. Tumor characterized by solid soft tissue mass 7 cases, 4 cases of cystic or solid mass. The density or signal of the most tumor was uneven, and 1 case lesion could be seen calcification. The majority of cases had a clear boundary. After contrast administration, moderate or marked homogeneous or heterogeneous enhancement, it was found. IMT occurred in abdominal cavity, abdominal wall and mesentery had invasive imaging features. The tumors were mainly composed of spindle shaped fibrous cells and inflammatory cells on pathology, and positive staining for muscle deriving proteins was observed immunohistochemically. The wave type protein (Vimentin) was positive in 10 patients, the smooth muscle actin (SMA) was positive in 8 patients, the muscle actin (MSA) was positive in 5 patients, and ALK, S-100 protein, CD117 and CD34 were all negative. Conclusion IMT is a rane tumor, and its imaging features hawe certain value for localization and qualitation diagnosis, but the diagnosis stiu needs to rely on pathological examination.
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