青年心肌梗死患者预后的影响因素

doi:10.20047/j.issn1673-7210.2023.20.18

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Abstract Objective To explore the influencing factors of prognosis of young patients with myocardial infarction. Methods A retrospective analysis was performed on 360 young patients with myocardial infarction who received treatment in Beijing Daxing District People’s Hospital from January 2020 to May 2022. All patients were followed up until November 2022. According to the occurrence of cardiogenic shock, heart failure, arrhythmia, angina pectoris after infarction, and death, the patients were divided into poor prognosis group (116 cases) and good prognosis group (244 cases). The clinical data of the two groups were compared. Logistic regression model was used to analyze the influnencing factors of prognosis of young patients with myocardial infarction. Results The heart rate, drinking proportion, Killip grade Ⅳ proportion, C-reactive protein, red cell volume distribution width, creatine kinase isozyme hybrid type, fibrinogen, myocardial troponin, and N-terminal brain natriuretic peptide precursor levels in the poor prognosis group were higher than those in the good prognosis group, and ejection fraction was lower than that in the good prognosis group, the differences were statistically significant (P＜0.05). The results of multivariate analysis showed that Killip grading (OR=1.672, 95%CI: 1.123-2.489), red cell volume distribution width (OR=2.319, 95%CI: 1.500-3.586), fibrinogen (OR=3.422, 95%CI: 1.123-2.489) were the influencing factors of poor prognosis in young patients with myocardial infarction (P＜0.05). Conclusion Killip grading, red blood cell volume distribution width, and fibrinogen are risk factors for poor prognosis in young patients with myocardial infarction, and patients with abnormal indexes should be closely monitored in clinical treatment.

Key words： Myocardial infarction Youth Prognosis Cardiovascular events Influencing factors

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	DONG Ningchao　WANG Wenbin　CHENG Guojie▲

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DONG Ningchao　WANG Wenbin　CHENG Guojie▲. Influencing factors of prognosis of young patients with myocardial infarction[J]. 中国医药导报, 2023, 20(20): 86-90.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.20.18 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I20/86

[1] 田春秀，张玉平.不同年龄段急性心肌梗死患者的临床特点分析及预后观察[J].中国药物与临床，2020，20（22）：3759-3760.
[2] 罗群华，黎明江，王鑫，等.冠状动脉非阻塞性心肌梗死的临床特征分析[J].中国医药导报，2020，17（5）：59-62.
[3] Corry DB，Eslami P，Yamamoto K，et al. Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system [J]. J Hypertension，2008，26（2）：269-275.
[4] Fang J，Alderman MH. Serum uric acid and cardiovascular mortality the NHANES Ⅰ epidemiologic follow-up study，1971-1992. National Health and Nutrition Examination Survey [J]. JAMA，2000，283（18）：2461-2462.
[5] 张瑞芳，王丽媛，郝金翠.老年高尿酸血症患者合并冠心病的风险评估及与冠脉病变的相关性[J].中国老年学杂志，2021，41（5）：913-916.
[6] Ioachimescu AG，Brennan DM，Hoar BM，et al. Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease：a preventive cardiology information system（PreCIS）database cohort study [J]. Arthritis Rheum，2008，58（2）：623-630.
[7] 罗艳兰，黄素兰，郭宁，等.青年急性心肌梗死患者发生院内并发症的危险因素研究[J].海南医学，2022，33（5）：554-558.
[8] 左惠娟，杨红霞，南楠，等.青年初发急性心肌梗死患者心肌梗死类型及危险因素变化趋势分析[J].中国循环杂志，2021，36（4）：329-334.
[9] 牛绍乾，张晓晴，汪雁博，等.青年与中老年急性ST段抬高型心肌梗死患者的临床特点及预后比较[J].中国循证心血管医学杂志，2021，13（9）：1100-1103.
[10] 岳博成，于洁，韩全乐，等.某地区中青年人群10年内急性心肌梗死的风险及危险因素分析[J].重庆医学，2020， 49（11）：1850-1854.
[11] 中国医师协会急诊医师分会，国家卫健委能力建设与继续教育中心急诊学专家委员会，中国医疗保健国际交流促进会急诊急救分会.急性冠脉综合征急诊快速诊治指南（2019）[J].临床急诊杂志，2019，20（4）：253-262.
[12] Werns SW，Bates ER. The enduring value of Killip classification [J]. Am Heart J，1999，137（2）：213-215.
[13] Orwat S，Diller GP. Congenital heart defects as an intrinsic additional risk factor for the occurrence and outcome of myocardial infarction [J]. Eur Heart J，2021，42（26）：2587- 2589.
[14] Wang F，Yu R，Wen S，et al. Overexpressing microRNA-203 alleviates myocardial infarction via interacting with long non-coding RNA MIAT and mitochondrial coupling factor 6 [J]. Arch Pharm Res，2021，44（5）：525-535.
[15] Wu N，Chen Y，Hou M. Level of von Willebrand factor to assess the occurrence and prognosis of acute myocardial infarction [J]. Ann Palliat Med，2021，10（10）：10444-10449.
[16] Kobayashi T，Nakamura T，Uematsu M，et al. Evaluation of renal tubulointerstitial damage as a residual renal risk factor for adverse cardiac events in patients with myocardial infarction [J]. J Cardiol，2021，78（2）：114-119.
[17] 孔羽，李全，万瑾，等.青年急性心肌梗死患者住院期间血尿酸水平与Killip分级严重程度的关系研究[J].心肺血管病杂志，2021，40（8）：795-798，808.
[18] 陈厚良，高彦琳，董玲玲，等.高NLR、Killip分级、PCI术后无复流对急性ST段抬高心肌梗死患者长期预后的影响[J].武警后勤学院学报（医学版），2019，28（11）：44-48.
[19] 沈健，张皓然，王枫，等.颈脑一体化超声联合红细胞分布宽度检测对冠心病的诊断价值[J].河北医学，2022， 28（11）：1869-1873.
[20] Machado GP，de Araujo GN，Carpes CK，et al. Long-term Pattern of Red Cell Distribution Width in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention [J]. Crit Pathw Cardiol，2020，19（1）：43-48.
[21] Dai C，Chen Z，Qian J，et al. Red Cell Distribution Width as a Marker of Periprocedural Myocardial Infarction in Patients with Elective Percutaneous Coronary Intervention [J]. J Cardiovasc Transl Res，2021，14（3）：449-456.
[22] Nakashima M，Sakuragi S，Miyoshi T，et al. Fibrosis-4 index reflects right ventricular function and prognosis in heart failure with preserved ejection fraction [J]. ESC Heart Fail，2021，8（3）：2240-2247.
[23] 张鸿雁，陈鑫森，张伟，等.血清Hcy联合血浆Fib对急性ST段抬高型心肌梗死患者PCI术后不良结局的预测价值[J].山东医药，2021，61（7）：82-86.
[24] 李瑞瑞，孙阳柳，邵东浦，等.青年首发急性心肌梗死患者危险因素分析[J].中国实验诊断学，2023，27（4）：450- 454.
[25] 莫健姣，黄显南，刘燕，等.青年急性心肌梗死发病危险因素的Meta分析[J].中国医学创新，2023，20（7）：162- 167.
[26] 卢静如，崔宗义，谢艳玲，等.青年急性心肌梗死患者临床危险因素及发病节律性研究[J].中国卫生工程学，2022， 21（6）：1016-1018.