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| Research progress on the correlation between irritable bowel syndrome with diarrhea and inflammatory immunity |
| WANG Xuejiao1 SUN Zhangyin2 JI Changchun3 |
1.College of Acupuncture, Moxibustion and Massage, Shaanxi University of Chinese Medicine, Shaanxi Province, Xianyang 712046, China;
2.the First Department of Acupuncture and Moxibustion, Shaanxi Hospital of Traditional Chinese Medicine, Shaanxi Province, Xi’an 710003, China
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Abstract Irritable bowel syndrome with diarrhea (IBS-D) is a functional intestinal disorder with recurrent abdominal pain, bloating, diarrhea, and a series of other gastrointestinal symptoms, which seriously affects the normal social life of patients, and causes serious psychological burden. The relationship between IBS-D and the immune system is complex, as IBS-D can affect the function of the immune system, and immune dysfunction can in turn affect the occurrence of IBS-D. This article reviews the alterations of the immune system in IBS-D patients and the effects of immune system disorders on IBS-D. We review the progress of research on the correlation between IBS-D and immune function from four perspectives: immune cells, immune factors, intestinal mucosal immunity, and immune homeostasis.
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