|
|
|
| Clinical effect of Zishen Runfei Liyan Decoction combined with press needle on chronic pharyngitis with syndrome of yin deficiency of lung and kidney |
| HU Qiao1 PU Chunping2 CHEN Linfeng1 WU Yongping2 |
1.Department of Otolaryngology, Nanchong Hospital of Traditional Chinese Medicine, Sichuan Province, Nnanchang 637000, China;
2.Department of Acupuncture, Nanchong Hospital of Traditional Chinese Medicine, Sichuan Province, Nnanchang 637000, China
|
|
|
|
Abstract Objective To explore the clinical effect of Zishen Runfei Liyan Decoction combined with press needle on chronic pharyngitis (CP) with syndrome of yin deficiency of lung and kidney. Methods A total of 135 patients with CP admitted to Nanchong Hospital of Traditional Chinese Medicine from January 2021 to July 2022 were selected and they were divided into three groups according to the random number table method. The decoction group was treated with Zishen Runfei Liyan Decoction, the press needle group was treated with press needle, and the combined group was treated with Zishen Runfei Liyan Decoction combined with press needle, all patients were treated for four weeks. The clinical efficacy, traditional Chinese medical syndrome scores, serum levels of interleukin-1β (IL-1β), IL-6, and tumor necrosis factor-α (TNF-α) were compared among the three groups before and after treatment, and the incidence rate of adverse reactions and recurrence were compared. Results The clinical effect of the combined group was better than that of the decoction group and the press needle group, the differences were statistically significant (P＜0.05). After treatment, the traditional Chinese medical symptom score and serum levels of IL-1β, IL-6, and TNF-α in combined group were lower than those in decoction group and press needle group, the differences were statistically significant (P＜0.05). No obvious adverse reactions occurred in the three groups. After three months of follow-up, the recurrence rate of combined group was lower than that of decoction group and press needle group, the difference was statistically significant (P＜0.05). Conclusion Zishen Runfei Liyan Decoction combined with press needle has a significant clinical effect on CP of lung-kidney yin deficiency type, which can effectively improve clinical symptoms, reduce the recurrence rate, and has high safety.
|
|
|
|
|
|
[1] 我国大气细颗粒物污染的急性健康风险及防治建议专家共识编写组，中华预防医学会环境卫生分会，中华医学会公共卫生分会.我国大气细颗粒物污染的急性健康风险及防治建议[J].中华医学杂志，2022，102（18）：1341- 1350.
[2] Zhao X，Lu M，An Z，et al. Acute effects of ambient air pollution on hospital outpatients with chronic pharyngitis in Xinxiang，China [J]. Int J Biometeorol，2020，64（11）：1923- 1931.
[3] 施磊，陈剑姝，张守杰，等.协定利咽茶防治慢性咽炎80例疗效观察[J].世界中西医结合杂志，2021，16（11）：2061- 2064.
[4] 李逸雪，刘恒瑞，付文洋.百合利咽茶治疗肺肾阴虚型慢喉痹的疗效及其网络药理学机制探讨[J].广州中医药大学学报，2022，39（7）：1542-1548.
[5] 王华，司丽，王艳丽，等.甘桔冰梅片联合布地奈德雾化吸入治疗慢性咽炎的临床研究[J].现代药物与临床，2021， 36（3）：498-501.
[6] 范梦月，张新雨，赵潇，等.经典名方及中成药治疗慢性咽炎疗效与安全性的网状Meta分析[J].药物评价研究，2021，44（4）：856-868.
[7] 田勇泉.耳鼻咽喉头颈外科学[M].8版.北京：人民卫生出版社，2013：7-10.
[8] 中华中医药学会.中医耳鼻咽喉科常见病诊疗指南[M].北京：中国中医药出版社，2011：29-30.
[9] 中华人民共和国国家标准（ZY/T001.1-94）：中医耳鼻喉科病证诊断疗效标准[S].中华人民共和国中医药行业标准，1994.
[10] 郑筱萸.中药新药临床研究指导原则（试行）[M].北京：中国医药科技出版社，2002：99-104.
[11] 中华医学会呼吸病学分会哮喘学组.咳嗽的诊断与治疗指南（2021）[J].中华结核和呼吸杂志，2022，45（1）：13- 46.
[12] 陈其冰，王燕，李芬，等.慢性咽炎病因和发病机制研究进展[J].听力学及言语疾病杂志，2019，27（2）：224-228.
[13] 杨艾，何旭东，张耀武，等.慢性咽炎的发病机制及药物治疗进展[J].中国药事，2021，35（7）：808-813.
[14] 叶哲，林基伟，吴海滨，等.王孟庸从肾论治慢性咽炎经验[J].中国中医药信息杂志，2021，28（3）：114-116.
[15] 隋博文，乔虎，付恒财，等.基于相火理论探讨慢性咽炎发病机制及治疗[J].吉林中医药，2021，41（10）：1276-1278.
[16] 梁芳妮，马燕辉，刘红玉，等.揿针主要临床应用研究进展[J].中医药导报，2019，25（11）：122-124.
[17] 张芹，张锋，李玲珑，等.揿针治疗咽喉疾病研究进展[J].实用中医药杂志，2022，38（7）：1271-1274.
[18] 解晓亚，袁军，安静，等. 特殊针刺天突穴配合刺络拔罐治疗急性咽炎临床研究[J]. 现代中西医结合杂志，2022， 31（6）：806-809.
[19] 刘雨娟，王莉，姚兰，等.TNF-α介导的NF-κB通路在沙尘导致大鼠慢性咽炎中的作用及射干对其影响[J].中国老年学杂志，2018，38（17）：4254-4256.
[20] 笈文娜，颜美秋，苏洁，等.铁皮石斛不同部位对辣椒水复合氨水刺激致慢性咽炎模型大鼠的作用研究[J].中国中药杂志，2022，47（9）：2525-2532.
[21] 严斐霞，谢永艳，陈畅，等.熟地黄炮制过程中的化学成分变化和药理作用研究进展[J].时珍国医国药，2021， 32（10）：2493-2495
[22] 邱晓月，景永帅，郑玉光，等.北沙参多糖对免疫系统调节作用研究进展[J].中国药理学与毒理学杂志，2021， 35（10）：794.
[23] 冯婉琳，李婧.牛蒡子的化学成分及心血管药理研究进展[J].内蒙古医科大学学报，2022，44（1）：101-104，112.
[24] 杨山景，封安杰，孙越，等.白芍总苷的药理作用及机制研究进展[J].中国现代应用药学，2021，38（13）：1627-1633.
[25] 陈秋彤，张雨桐，鄢琬霖，等.揿针治疗儿童变应性鼻炎作用机制研究进展[J/OL].实用中医内科杂志：1-5[2023-02-24]. http：//kns.cnki.net/kcms/detail/21.1187.R.20221108.1200.004.html.
[26] 项少茜，胡晓雷.腕踝针联合揿针疗法治疗腰腿痛患者的临床效果[J].中国医药导报，2022，19（16）：147-150.
[27] 韩翠影，张春菊.俞募配穴法中药敷贴联合耳穴揿针对胸痹心痛症患者的护理干预效果[J].中国医药科学，2022，12（13）：147-150，166.
[28] 环林林，王乐红，顾玉华，等.揿针对改善卒中后疲劳患者疲劳程度、生活质量及运动功能的效果[J].中国临床研究，2022，35（4）：581-585. |
|
|
|
