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Analysis of clinical application of in vitro fertilization-embryo transfer acupuncture stage adjuvant treatment based on “nourishing kidney and blood” |
WU Jiaman1 MA Fei1 LI Yitong1 TAN Liya2 LIN Yanting1 NING Yan1 |
1.Shenzhen Maternity and Child Healthcare Hospital Affiliated to Southern Medical University, Guangdong Province, Shenzhen 518028, China;
2.Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510405, China
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Abstract Assisted reproductive technology is one of the modern mainstream diagnosis and treatment methods for the infertility. However, its success rate is low and there are also many complications in the process of follicle extraction and transplantation. Multidisciplinary integration is the trend of current medical development. In this paper, starting from the perspective of acupuncture and moxibustion assisted treatment, according to the reproductive physiological characteristics of in vitro fertilization-embryo transfer at different time nodes, it is divided into six stages: pre-in vitro fertilization conditioning period, pituitary down-regulation period, controlled superovulation period, ovulation period, pre-embryo transfer period, and post-transplantation period. In this paper, staging and syndrome differentiation treatment of traditional Chinese and western medicine is adopted, and a unique set of acupuncture and moxibustion auxiliary treatment program of “nourishing kidney and blood” is constructed from the perspective of acupuncture and moxibustion auxiliary treatment program, in order to provide a relatively safe and effective treatment method to improve the rate of fertilization, embryo implantation rate and pregnancy rate of clinical in vitro fertilization-embryo transfer patients, while reducing the amount of drugs and toxic side effects.
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[1] 邓君瑜,林金玉,熊欢.我国育龄妇女综合健康状况及影响因素分析[J].中国健康教育,2021,37(8):675-679.
[2] 中华医学会.临床诊疗指南:辅助生殖技术与精子库分册[M].临床诊疗指南:辅助生殖技术与精子库分册,2009.
[3] Thompson WE,Asselin E,Branch A,et al. Regulation of prohibitin expression during follicular development and atresia in the mammalian ovary [J]. Biol Reprod,2004,71(1):282- 290.
[4] 徐金龙,赵荣,杨增荣,等.针刺在辅助生殖领域中的临床研究概述[J].上海针灸杂志,2018,37(7):827-832.
[5] 张良,张建伟,吴海萃,等.中医药在辅助生殖技术中的研究进展[J].中华中医药学刊,2020,38(11):81-84.
[6] 卓缘圆,杨卓欣,张金文,等.针刺治疗早发性卵巢功能不全60例[J].中国针灸,2019,39(7):778-780.
[7] 吴家满,宁艳,陈瑜,等.调经促孕针法治疗卵巢早衰的临床疗效观察[J].时珍国医国药,2019,30(6):1422-1423.
[8] 尹萍,李丽,路璐,等.针刺联合辅助生殖技术对多囊卵巢综合征患者临床妊娠结局影响的Meta分析及GRADE质量评价[J].中华中医药杂志,2020,35(2):854- 858.
[9] 阎梦,华芮,周瑶,等.长方案控制性超促排卵过程中黄体生成素水平对多囊卵巢综合征患者IVF-ET结局的影响[J].南方医科大学学报,2016,36(3):381-385.
[10] 李元,龚斐.重组人黄体生成素能改善改良超长方案多囊卵巢综合征患者IVF/ICSI妊娠结局[J].生殖医学杂志,2015,24(1):21-25.
[11] 沈鉴东,孙方西,瞿殿云,等.妊娠早期自然流产组织染色体异常情况及其相关因素分析[J].中华妇产科杂志,2019,54(12):797-802.
[12] 李颖,兰永连,梁毓,等.卵巢低反应高龄患者体外受精-胚胎移植的不同促排卵方案比较[J].中国优生与遗传杂志,2018,26(2):80-90,111.
[13] 夏庆昌,高树中,马玉侠,等.针灸防治反复种植失败的研究进展[J].时珍国医国药,2021,32(12):2990-2994.
[14] 周莉,夏有兵,马翔,等.针灸序贯疗法在辅助生殖中的应用,优势与展望[J].中华中医药杂志,2016,31(7):2476-2478.
[15] 王璐璐.3种降调长方案对卵巢储备功能正常不孕患者IVF/ICSI促排卵效果的比较性研究[J].现代妇产科进展,2019,28(8):597-601.
[16] 焦婷婷,李建华,张水文,等.GnRH-a短方案与PPOS方案在高龄卵巢储备功能减退不孕症治疗中的应用对比观察[J].山东医药,2022,62(26):75-78.
[17] 黄柳菁.卵巢储备功能减退患者在IVF/ICSI中PPOS方案及拮抗剂方案应用比较[D].南宁:广西医科大学,2019.
[18] 陈智勤,潘家坪,滕晓明.微刺激方案在常规IVF-ET治疗失败后卵巢低反应患者中的应用[J].生殖与避孕,2012,32(7):464-469.
[19] 马娟娟,伍奇,吕云佳,等.针刺改善体外受精-胚胎移植冻胚移植患者围移植期子宫内膜蠕动波及妊娠结局的随机对照研究[J].上海中医药大学学报,2022,36(5):27-33.
[20] 杨泽欣,白雪莲,范亚珍,等.PCOS患者胚胎质量以及解冻移植周期妊娠结局影响因素分析[J].中华生殖与避孕杂志,2021,42(4):357-363.
[21] 陈滢如,李春华,赵丹.针灸辅助生殖功能的国内研究进展[J].上海针灸杂志,2019,38(5):578-582.
[22] 章小娟,赵锐,陈阳,等.揿针在体外受精-胚胎移植经阴道超声穿刺取卵术中镇痛的应用[J].中国临床研究,2022,35(2):230-233.
[23] 卓缘圆,黄杏贤,黄奕珊,等.调经促孕针刺法治疗早发性卵巢功能不全行体外受精-胚胎移植术患者的效果[J].中国医药导报,2021,18(15):125-128,132.
[24] 宁艳,刘新玉,冯倩怡,等.罗颂平运用中药分期介入辅助生殖技术的临证思路[J].中医药导报,2020,26(11):187-189.
[25] 宁艳,宁晔,陈雪玲,等.补肾活血中药配合强的松治疗抗精子抗体阳性不孕患者临床观察[J].新中医,2010,(7):37-38,7.
[26] 金笑天,江涵,吕赟,等.女性卵巢储备功能下降的危害因素及中医体质类型分布[J].中国妇幼保健,2021,36(21):4986-4989.
[27] 贾静,马小娜.补肾活血通络法治疗薄型子宫内膜经验[J].环球中医药,2020,13(9):1574-1576.
[28] 丘维钰,郜洁,高飞霞,等.“肾—天癸—冲任—胞宫”生殖轴的研究进展[J].广州中医药大学学报,2017,34(6):945-947.
[29] 吴家满,卓缘圆,叶杨阳,等.调任通督针法治疗多囊卵巢综合征不孕症临床思路与方法探析[J].中国医药导报,2020,17(1):130-133.
[30] 杨松青,周黎明,王丽萍,等.高孕激素状态促排卵与拮抗剂方案在卵巢储备功能减退的年轻人群中体外受精-胚胎移植结局比较[J].中国医药科学,2021,11(1):8- 12.
[31] Wu JM,Ning Y,Ye YY,et al. Effects of Acupuncture on End- ometrium and Pregnancy Outcomes in Patients with Polycystic Ovarian Syndrome Undergoing in vitro Fertilization-Embryo Transfer:A Randomized Clinical Trial [J]. Chin J Integr Med,2022,28(8):736-742. |
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