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| Patent analysis of CAR-NK cell therapy technology |
| LIANG Yaru1 LI Liyuan2 |
1.National Intellectual Property Administration, Beijing 100088, China;
2.Ministry of Education, Key Laboratory of Protein Science, School of Pharmacy, Tsinghua University, Beijing 100084, China
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Abstract Objective To reveal the research progress of CAR-NK cell therapy from the perspective of patents, in order to provide useful references for further research of innovative entities in our country. Methods CAR-NK related patents are searched through the database of China Patent Search and Service System, and the development trend, regional distribution and the research and development route of main applicants in the field were analyzed. Results The number of CAR-NK patent applications was growing steadily. At present, many domestic and foreign companies were accelerating their deployment in this field. The research of domestic companies mainly focused on the design of CAR-NK with different targets, and involves less combination drugs and upstream and downstream technologies. The technical direction of patent application distribution was relatively simple and was in the relatively initial stage of research and development, while the patent applications of foreign large pharmaceutical companies, focused on multi-angle layout, involving all aspects of the industrial chain. Conclusion The number of high-value patents in the field of CAR-NK in our country is relatively small, and more attention needs to be paid to patent layout and achievement transformation in the future.
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