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A case of giant esophageal gastrointestinal stromal tumor and literature review |
LUO Lei1 ZHANG Yue’e2 YANG Yanhui1 LI Ji1 XIE Xiaoyang1 LIU Caiyang1 LEI Yu1 WANG Yi1 |
1.Department of Cardiothoracic Surgery, the First People’s Hospital of Neijiang, Sichuan Province, Neijiang 641000, China;
2.Department of Nephrology, the First People’s Hospital of Neijiang, Sichuan Province, Neijiang 641000, China
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Abstract Gastrointestinal stromal tumor (GIST) are a relatively rare of gastrointestinal diseases, and oesophageal GIST is even rarer. A case of giant esophageal stromal tumor admitted to the First People’s Hospital of Neijiang, Sichuan Province (hereinafter referred to as “our hospital”) was retrospectively analyzed, the tumor size was 10.7 cm×7.9 cm×1.6 cm. The main symptom of the patient was dysphagia obstruction, which was misdiagnosed as “advanced esophageal cancer” in the past and failed to receive timely surgical treatment, the patient was successfully treated by right thoracic and abdominal incision (Ivor Lewis surgery) in the Department of Cardiothoracic Surgery of our hospital. The postoperative pathological diagnosis was GIST. According to the plan, the patient ate normally on the 7th day after surgery and was discharged successfully on the 10th day after surgery. Therefore, comprehensive treatment such as preoperative comprehensive evaluation, individualized surgical plan and postoperative targeted drug-assisted therapy can help improve GIST patients’ quality of life and prolong survival rate. Therefore, this paper reviewed the literature on the origin, diagnosis, and treatment of GIST in order to improve the attention of clinicians to this disease.
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[1] Tangkittikasem N,Boonyaarunnate T,Aswakul P,et al. Clinical,Radiologic,and Endoscopic Manifestations of Small Bowel Malignancies:a First Report from Thailand [J]. Asian Pac J Cancer Prev,2015,16(18):8613-8618.
[2] Iruzubieta P,Monzón M,Castiella T,et al. Hedgehog signalling pathway activation in gastrointestinal stromal tumours is mediated by primary cilia [J]. Gastric Cancer,2020,23(1): 64-72.
[3] Panbude SN,Ankathi SK,Ramaswamy AT,et al. Gastrointestinal Stromal Tumor (GIST) from esophagus to anorectum- diagnosis,response evaluation and surveillance on computed tomography (CT) scan [J]. Indian J Radiol Imaging,2019,29(2):133-140.
[4] Joensuu H,Hohenberger P,Corless CL. Gastrointestinal str- omal tumor [J]. Lancet,2013,382(9896):973-983.
[5] Rubin BP,Heinrich MC,Corless CL. Gastrointestinal stromal tumor [J]. Lancet,2007,369(9574):1731-1741.
[6] National Comprehensive Cancer Network. Gastrointestinal Str- omal Tumors (GISTs),Version 1,2021. Debiec-Rychter M. Gastrointestinal Stromal Tumors (GISTs)[M]. John Wiley & Sons,Ltd,2009.
[7] Gopie P,Mei L,Faber AC,et al. Classification of gastrointestinal stromal tumor syndromes [J]. Endocr Relat Cancer,2018,25(2):R49-R58.
[8] Poveda A,García Del Muro X,López-Guerrero JA,et al. GEIS guidelines for Gastrointestinal Sarcomas (GIST) [J]. Cancer Treat Rev,2017,55(7):107-119.
[9] 张鹏,陶凯雄,王国斌.开展胃肠间质瘤相关临床研究的启示[J].中国实用外科杂志,2022,42(4):394-397.
[10] 杨舒雅,叶颖江,高志冬.琥珀酸脱氢酶缺陷型胃肠间质瘤研究进展[J].中国实用外科杂志,2022,42(3):344-348.
[11] Alawawdeh F,Al-Tkrit A,Aneeb M,et al. Gastrointestinal Stromal Tumor:An Uncommon but Serious Cause of Gastrointestinal Bleeding [J]. J Med Cases,2021,12(2):74-78.
[12] 崔仪,韩振国.胃肠道间质瘤治疗的研究进展[J].中国医药导报,2020,17(1):42-45.
[13] 田涛.免疫组化标记物联合检测在胃肠道间质瘤病理学诊断中的价值观察[J].当代医学,2021,27(21):162- 164.
[14] Kadado KJ,Abernathy OL,Salyers WJ,et al. Gastrointestinal Stromal Tumor and Ki-67 as a Prognostic Indicator [J]. Cureus,2022,14(1):e20868.
[15] 聂涵笑,贺涛,王莉,等.右上腹巨大胃肠间质瘤肝转移伴急性上消化道出血1例报道[J].胃肠病学和肝病学杂志,2021,30(2):238-240.
[16] 王燕,黄晓俊.胃肠道间质瘤的诊断策略及其临床价值分析[J].现代消化及介入诊疗,2021,26(3):397-401, 405.
[17] 王芳芳,韩宇,张彩凤.胃肠道间质瘤的研究进展[J].现代消化及介入诊疗,2021,26(10):1318-1322.
[18] Mastoraki A,Toliaki E,Chrisovergi E,et al. Metastatic Liver Disease Associated with Gastrointestinal Stromal Tumors:Controversies in Diagnostic and Therapeutic Approach [J]. J Gastrointest Cancer,2015,46(3):237-242.
[19] 王浩,范小华,梁学敏,等.肛周胃肠间质瘤1例[J].现代消化及介入诊疗,2021,26(6):800-801.
[20] Navarrete A,Momblán D,Almenara R,et al. Giant gastric gastrointestinal stromal tumor (GIST) [J]. J Gastrointest Surg, 2017,21(1):202-204.
[21] Akahoshi K,Oya M,Koga T,et al. Current clinical management of gastrointestinal stromal tumor [J]. World J Gastroenterol,2018,24(26):2806-2817.
[22] Coccolini F,Catena F,Ansaloni L,et al. Esophagogastric junction gastrointestinal stromal tumor:Resection vs enucleation [J]. World J Gastroenterol,2010,16(35):4374- 4376.
[23] 曹晖,高志冬,何裕隆,等.胃肠间质瘤规范化外科治疗中国专家共识(2018版)[J].中国实用外科杂志,2018, 38(9):965-973.
[24] Call J,Walentas CD,Eickhoff JC,et al. Survival of gastrointestinal stromal tumor patients in the imatinib era:life raft group observational registry [J]. BMC Cancer,2012,12(3):90.
[25] 李龙泉,王永庆,马明,等.胃肠道间质瘤治疗进展[J].医学综述,2021,27(8):1539-1544.
[26] CSCO胃肠间质瘤专家委员会.中国胃肠间质瘤诊断治疗共识(2013 年版)[J].临床肿瘤学杂志,2013,18(11):1025-1032.
[27] Watson GA,Kelly D,Melland-Smith M,et al. Get the GIST An overview of Gastrointestinal Stromal Tumors [J]. Ir J Med Sci,2016,185(2):319-326.
[28] Balachandran VP,DeMatteo RP. Gastrointestinal stromal tumors:who should get imatinib and for how long? [J]. Adv Surg,2014,48(1):165-183. |
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