非川崎病发热性疾病致冠状动脉瘤2例并文献分析

doi:10.20047/j.issn1673-7210.2023.18.37

Abstract
Figure/Table
References (37)
Related Citation (15)

Download: PDF (1225 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Kawasaki disease is not the only disease that causes coronary artery lesions (CAL) in children. Takayasu arteritis (TA) and systemic onset juvenile idiopathic arthritis (SOJIA) can also involve coronary arteries, which are relatively rare in clinic and easy to miss/misdiagnose. This paper reports a case of fever with coronary artery aneurysm (CAA) who was not well treated with intravenous immunogloblin (IVIG). High blood pressure, subclavian artery stenosis, and axillary artery aneurysm were found in the course of diagnosis and treatment. TA was finally diagnosed and relieved after treatment with Prednisone, Methotrexate, and Tocilizumab. This paper also reports a patient with SOJIA, who was hospitalized mainly due to fever and CAA. The efficacy of IVIG was poor, and then rash and multiple joint effusion (hip, knee, and shoulder joints) occurred. The patient was diagnosed as SOJIA and improved after treatment with Naproxen Tablets, Hormones and Tocilizumab. This article retrospectively reviewed the clinical features of two cases of CAA caused by non-Kawasaki disease febrile disease, in order to improve the understanding of clinical doctors of the diseases related to CAL in children.

Key words： Coronary artery aneurysm Non-Kawasaki disease febrile illness Kawasaki disease Children

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	WANG Yingxue1 CHEN Jingshi1 JIA Yuhan2 ZHENG Yumeng2 ZHANG Yingqian1▲

Cite this article:

WANG Yingxue1 CHEN Jingshi1 JIA Yuhan2 ZHENG Yumeng2 ZHANG Yingqian1▲. Non-Kawasaki disease febrile illness complicated coronary artery aneurysm in two cases and the literature review[J]. 中国医药导报, 2023, 20(18): 164-168,173.

URL:

https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.18.37 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I18/164

[1] McCrindle BW，Rowley AH，Newburger JW，et al. Diagnosis，Treatment，and Long-Term Management of Kawasaki Disease：A Scientific Statement for Health Professionals From the American Heart Association [J]. Circulation，2017，135（17）：e927-e999.
[2] 中华医学会儿科学分会心血管学组，中华医学会儿科学分会风湿学组，中华医学会儿科学分会免疫学组，中华儿科杂志编辑委员会.川崎病诊断和急性期治疗专家共识[J].中华儿科杂志，2022，60（1）：6-13.
[3] 中华医学会儿科学分会心血管学组，中华儿科杂志编辑委员会.川崎病冠状动脉病变的临床处理建议（2020年修订版）[J].中华儿科杂志，2020，58（9）：718-724.
[4] Lee M，Meidan E，Son M，et al. Coronary artery aneurysms in children is not always Kawasaki disease：a case report on Takayasu arteritis [J]. BMC Rheumatol，2021，5（1）：27.
[5] Brunner J，Feldman BM，Tyrrell PN，et al. Takayasu arteritis in children and adolescents [J]. Rheumatology （Oxford），2010， 49（10）：1806-1814.
[6] Ruperto N，Ozen S，Dolezalova P，et al. EULAR/PRINTO/ PRES criteria for Henoch-Sch?觟nlein purpura，childhood polyarteritis nodosa，childhood Wegener granulomatosis and childhood Takayasu arteritis：Ankara 2008. Part Ⅰ：Overall methodology and clinical characterization [J]. Ann Rheum Dis，2010，69（5）：790-797.
[7] 张丹，赖建铭，孙雪峰，等.婴幼儿多发性大动脉炎14例临床特点分析[J].中华实用儿科临床杂志，2020，35（1）：27-31.
[8] Reddy SM，Reddy SP. Stenosis of the main stem of the left coronary artery in a teenager with Takayasu’s arteritis [J]. Cardiol Young，2009，19（6）：638-640.
[9] Berman DP，Lewis AB，Kung GC. Case Report of a 2-year-old boy with Takayasu’s arteritis：an atypical，severe presentation of a rare disease [J]. Pediatr Cardiol，2010，31（7）：1089-1092.
[10] Mohan S，Poff S，Torok KS. Coronary artery involvement in pediatric Takayasu’s arteritis：Case report and literature review [J]. Pediatr Rheumatol Online J，2013，11（1）：4.
[11] Russo RAG，Katsicas MM. Takayasu Arteritis [J]. Front Pediatr，2018，6：265.
[12] Sreih AG，Alibaz-Oner F，Kermani TA，et al. Development of a Core Set of Outcome Measures for Large-vessel Vasculitis：Report from OMERACT 2016 [J]. J Rheumatology，2017，44（12）：1933-1937.
[13] Fan L，Zhang H，Cai J，et al. Clinical course and prognostic factors of childhood Takayasu’s arteritis：over 15-year comprehensive analysis of 101 patients [J]. Arthritis Res Ther，2019，21（1）：31.
[14] 屠志强，李晓忠.儿童危重多发性大动脉炎的诊治进展[J].中国小儿急救医学，2020，27（5）：336-340.
[15] 李彩凤，黄新翔，王永福，等.幼年特发性关节炎诊疗规范[J].中华内科杂志，2022，61（2）：142-156.
[16] Lefèvre-Utile A，Galeotti C，Koné-Paut I. Coronary artery abnormalities in children with systemic-onset juvenile idi- opathic arthritis [J]. Joint Bone Spine，2014，81（3）：257-259.
[17] Binstadt BA，Levine JC，Nigrovic PA，et al. Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis [J]. Pediatrics，2005，116（1）：e89-e93.
[18] Shin JI，Choi JY，Kim DS. Comment on failure to distinguish systemic-onset juvenile idiopathic arthritis from incomplete Kawasaki disease in an infant [J]. J Paediatr Child Health，2008，44（11）：677-678.
[19] Silverman ED，Cawkwell GD，Lovell DJ，et al. Intravenous immunoglobulin in the treatment of systemic juvenile rheu- matoid arthritis：a randomized placebo controlled trial. Pediatric Rheumatology Collaborative Study Group [J]. J Rhe Umatol，1994，21（12）：2353-2358.
[20] 王凤，桂永浩.不完全川崎病的临床诊治策略[J].国际儿科学杂志，2007，34（6）：436-439.
[21] 王琍，林毅，苏英姿，等.283例川崎病的临床分析[J].中华儿科杂志，2004，42（8）：609-612.
[22] Xiao H，Hu B，Luo R，et al. Chronic active Epstein-Barr virus infection manifesting as coronary artery aneurysm and uveitis [J]. Virol J，2020，17（1）：166.
[23] 谢小斐，卢根，黄萍，等.慢性活动性EB病毒感染并冠状动脉瘤4例并文献复习[J].中华实用儿科临床杂志，2016，31（22）：1721-1727.
[24] 邵魏，袁越.幼儿慢性活动性EB病毒感染合并冠状动脉瘤1例[J].中华实用儿科临床杂志，2016，31（22）：1752- 1753.
[25] Rouva G，Vergadi E，Hatzidaki E，et al. Mild coronary artery dilatation developed in some children with mild COVID-19 but completely regressed within 3 months [J]. Acta Paediatr，2022，111（9）：1764-1770.
[26] Wacker J，Malaspinas I，Aggoun Y，et al. Coronary artery dilatation in a child with hyperinflammatory syndrome with SARS-CoV-2-positive serology [J]. Eur Heart J，2020，41（32）：3103.
[27] Pick J，Rao MY，Dern K，et al. Coronary Artery Changes in Patients with Multisystem Inflammatory Syndrome in Children：Los Angeles Experience [J]. J Pediatr，2022，240：292-296.
[28] Al Qahtani M，Uddin MS，Al Fulayyih S，et al. An 11-Year- Old Saudi Arabian Girl Who Presented with Multisystem Inflammatory Syndrome in Children （MIS-C） Associated with SARS-CoV-2 Infection with Coronary Artery Aneurysm and Cardiac Involvement：A Case Report [J]. Am J Case Rep，2021，22：e933053.
[29] Ford SR，Rao A，Kochilas L. Giant coronary artery aneu- rysm formation following meningococcal septicaemia [J]. Pediatr Cardiol，2007，28（4）：300-302.
[30] van Doorn HR，Lo-A-Njoe SM，Ottenkamp J，et al. Widened coronary arteries in a feverish child [J]. Pediatr Cardiol, 2006，27（4）：515-518.
[31] Williams-Phillips S. Marfan’s syndrome：pre-pubertal aortic rupture with left coronary artery aneurysms and fistulas [J]. West Indian Med J，2012，61（9）：937-940.
[32] Liu C，Epelman MS，Ten I，et al. Isolated Coronary Artery Aneurysm in a 12-Year-Old Boy With Marfan Syndrome [J]. Tex Heart Inst J，2021，48（4）：e186932.
[33] Iwasaki Y，Horigome H，Takahashi-Igari M，et al. Coronary artery dilatation in LEOPARD syndrome. A child case and literature review [J]. Congenit Heart Dis，2009，4（1）：38-41.
[34] Simry W，Al Kindi H，Sedky Y，et al. Congenital Coronary Aneurysm：Unusual Presentation of Myocardial Ischemia in Children [J]. World J Pediatr Congenit Heart Surg，2021，12（1）：133-135.
[35] Tahouri T，Mahdavi M，Rezaei-Kalantari K，et al. Irreversible coronary aneurysm presenting as acute coronary syndrome in a child with hypereosinophilic syndrome：a case report [J]. Cardiol Young，2021，31（5）：845-847.
[36] Muniz JC，Dummer K，Gauvreau K，et al. Coronary artery dimensions in febrile children without Kawasaki disease [J]. Circ Cardiovasc Imaging，2013，6（2）：239-244.
[37] Rangaswamy D，Ramamoorthy JG，Mukarjee S，et al. All That Childhood Coronary Artery Aneurysms Are Not Kawasaki Disease! [J]. Indian J Pediatr，2021，88（1）：97-98.