|
|
Effect of Kangfuxin Liquid on patients with moderate chronic periodontitis |
LIU Jing DONG Hongbin TIAN Mengting ZHAO Jingyao |
Department of Prosthodontics and Implant, First Affiliated Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830000, China
|
|
|
Abstract Objective To investigate the effect of Kangfuxin Liquid on patients with moderate chronic periodontitis. Methods A total of 80 patients with moderate chronic periodontitis admitted to the First Affiliated Hospital of Xinjiang Medical University from September 2020 to December 2021 were selected and divided into treatment A group (40 cases) and treatment B group (40 cases) by random number table method. The treatment A group was treated with scaling and root planning (SRP) and Kangfuxin Liquid, and the treatment B group was treated with SRP and Xipayi Guyin Ye. Both groups were treated continuously for one month. The changes of periodontal indexes, inflammatory factors, and oxidative stress indexes were compared between the two groups before and after treatment. Results After treatment, the plaque index, sulcus bleeding index, probing depth, clinical attachment loss level, tumor necrosis factor-α, interleukin-6, and malondialdehyde in the two groups were lower than those before treatment, and those in the treatment A group were lower than those in the treatment B group, and the differences were statistically significant (P<0.05). Conclusion Kangfuxin Liquid combined with SRP in the treatment of moderate chronic periodontitis can improve the periodontal indexes of patients, reduce the inflammatory response and oxidative stress response of periodontal tissue, and promote the recovery of periodontal tissue. The effect is better than Xipayi Guyin Ye.
|
|
|
|
|
[1] 闫福华.牙周炎对全身疾病和健康影响的研究进展[J].口腔医学,2018,38(7):577-581.
[2] 唐雯静.益生菌辅助SRP治疗慢性牙周炎疗效的系统评价和Meta分析[D].重庆:重庆医科大学,2020.
[3] Smiley CJ,Tracy SL,Abt E,et al. Evidence-based clinical practice guideline on the nonsurgical treatment of chronic periodontitis by means of scaling and root planing with or without adjuncts [J]. J Am Dent Assoc,2015,146(7):525- 535.
[4] 李瑛琦,张煜培,王晨茜,等.慢性牙周炎的中医药治疗研究进展[J].中国美容医学,2021,30(10):178-181.
[5] 宁海燕,梁斌,梁扬师.西帕依固龈液含漱或冲洗辅助牙周基础治疗对牙周炎疗效的对比研究[J].实用口腔医学杂志,2020,36(2):312-316.
[6] 陈明铭,王敏娜,廖湘凌.康复新液结合常规疗法治疗慢性牙周炎临床研究[J].上海中医药杂志,2017,51(2):61-63.
[7] 束蓉,倪靖.2018牙周病和植体周病国际新分类——牙周炎分期分级疾病定义系统临床应用体会[J].口腔医学,2020,40(1):1-6.
[8] 金泽高.两种抗生素联合方式用于牙周炎治疗的疗效及不良反应比较[J].海峡药学,2019,31(6):249-251.
[9] 李瑛琦,张煜培,王晨茜,等.慢性牙周炎的中医药治疗研究进展[J].中国美容医学,2021,30(10):178-181.
[10] 李新尚,牛巧丽,赵今.基于数据挖掘、网络药理学和分子对接的中药治疗牙周疾病的用药规律与作用机制[J].口腔疾病防治,2022,30(7):464-474.
[11] 吕娜.美洲大蠊化学成分及其制剂康复新液的质量控制研究[D].北京:北京协和医学院,2017.
[12] 张汉超,耿福能,沈咏梅,等.康复新液药理作用及临床应用的研究进展[J].中国民族民间医药,2017,26(3):57-60.
[13] 陈明铭,王敏娜,廖湘凌.康复新液结合常规疗法治疗慢性牙周炎临床研究[J].上海中医药杂志,2017,51(2):61-63.
[14] 高媛.两种口含液不同用法对牙周炎患者疗效的比较[D].石家庄:河北医科大学,2013.
[15] 蔡鉴,朱婵媛.康复新液对慢性牙周炎患者牙周状况及龈沟液炎性因子水平的影响[J].药品评价,2021,18(11):677-679.
[16] 才新.超声刮治联合康复新液对慢性牙周炎患者龈沟液IL-8、MMP-8、TIMP-1水平的影响[J].当代医学,2021, 27(11):169-170.
[17] 荣培华,冯承水.康复新液辅助龈下刮治和根面平整治疗慢性牙周炎的效果[J].中国民康医学,2021,33(14):51-52.
[18] 马璇,范晨阳,季志红,等.西帕依固龈液成分鉴定及其治疗复发性阿弗他溃疡作用机制的网络药理学研究[J].中国药业,2022,31(2):41-45.
[19] 斯拉甫,努尔买买提·艾买提,阿布都热依木·玉苏甫,等.维药西帕依固龈液的药理作用研究[J].中国民族医药杂志,1999(3):37-38.
[20] 刘春子,潘艳,米宏图.西帕依固龈液漱口结合牙周基础治疗对糖尿病合并牙周炎患者的疗效观察[J].实用口腔医学杂志,2020,36(4):605-608.
[21] 徐倩.西帕依固龈液辅助治疗中重度牙周炎的疗效评价[J].齐齐哈尔医学院学报,2020,41(17):2192-2194.
[22] 宁海燕,梁斌,梁扬师.西帕依固龈液对慢性牙周炎患者牙周指标和龈沟液中细胞因子的影响[J].中国医药,2019,14(4):600-604.
[23] 肖兵,姚永泽,张辉,等.西帕依固龈液联合牙周基础治疗对2型糖尿病并发牙周炎患者的临床效果分析[J].中国医药,2020,15(2):248-250.
[24] 李颖,孙江.西帕依固龈液联合牙周基础疗法治疗老年慢性牙周炎的临床观察[J].航空航天医学杂志,2021, 32(2):175-177.
[25] 黄平.两种口含液不同用法对牙周炎患者疗效对比[J].全科口腔医学电子杂志,2016,3(7):38-39. |
|
|
|