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| Effects of corn silk aqueous extract on glucose and lipid metabolism and liver and kidney function in newly diagnosed mild type 2 diabetic elderly patients |
| CHENG Yu1，2 YANG Wenqin1 CHAO Hong1 QI Lei1 ZHOU Zhongguang2 LIU Jicheng1，2 GUAN Hong1 |
1.School of Public Health, Qiqihar Medical University, Heilongjiang Province, Qiqihar 161006, China;
2.Postdoctoral Workstation, Research Institute of Medical and Pharmacy, Heilongjiang Province, Harbin 150000, China
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Abstract Objective To investigate the effect of corn silk aqueous extract on glucose and lipid metabolism, liver and kidney function in newly diagnosed mild type2 diabetes mellitus (T2DM) elderly patients. Methods A total of 72 newly diagnosed mild T2DM elderly patients were recruited from the Second Affiliated Hospital of Qiqihar Medical College from June to October 2020, and they were divided into intervention group and control group by random number table method, with 36 cases in each group. The patients in the intervention group took 4.8 g corn silk aqueous extract every day, and the control group was given the same amount of toast powder as placebo. The indexes of glucose and lipid metabolism, liver, and kidney function were compared between the two groups. Results After treatment, fasting insulin, insulin resistance index, alanine aminotransferase, and aspartate aminotransferase in the intervention group were lower than before treatment, insulin sensitivity index, and total bilirubin were higher than before treatment, fasting blood glucose in the control group was higher than before treatment, and fasting blood glucose, fasting insulin, insulin resistance index, total cholesterol, aspartate aminotransferase and total bilirubin in the intervention group were lower than before treatment, insulin sensitivity index was higher than control group, the differences were statistically significant (P＜0.05). Conclusion The intervention of corn silk aqueous extract can improve fasting blood glucose and insulin resistance, regulate blood lipid, have no adverse effect on liver and kidney function in elderly patients with newly diagnosed mild T2DM.
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