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Research progress on the correlation between fibrinogen and diabetic nephropathy |
ZHANG Xinyu1 TIAN Fengsheng2▲ |
1.Graduate School, Hebei University of Chinese Medicine, Hebei Province, Shijiazhuang 050091, China;
2.Department of Endocrine Diabetes, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Hebei University of Chinese Medicine, Hebei Province, Cangzhou 061001, China
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Abstract Diabetic nephropathy (DN) is one of the chronic complications of diabetes mellitus, which can easily lead to renal failure and finally develop into end-stage renal disease. Fibrinogen (FIB) is an important substance before thrombosis, and its elevated level indicates hypercoagulation. With the progression of DN, the risk of thrombosis increases and cardiovascular disease is easy to be complicated. The occurrence of cardiovascular events is one of the causes of death in DN patients. This paper reviews recent studies on the correlation between FIB and DN, aiming to explore the current research status of the relationship between FIB and DN, to elaborate the important clinical significance of detecting FIB in the diagnosis and treatment of DN patients, and to provide support for preventing thrombosis and reducing the risk of cardiovascular events in patients with DN.
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