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Research progress on the relationship between oral flora and oral diseases and systemic diseases |
ZHU Shuang TANG Shuai DING Gang |
School of Stomatology, Weifang Medical University, Shandong Province, Weifang 261053, China
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Abstract Oral cavity is a complex multi-microbial environment. A wide variety of microorganisms form oral flora, which constitutes the oral microecosystem together with the oral environment. Oral flora can be affected by many factors, such as gender, age, race, and living habits, etc., and plays an important role in maintaining oral and general health, and the occurrence and development of diseases. The development of high-throughput sequencing technology and bio-information technology has laid a foundation for the comprehensive study of oral flora. Accordingly, the structure and function of oral flora and its relationship with human health and disease are increasingly clear. This article reviews the research progress of oral flora, its association with oral diseases and systemic diseases, and looks forward to the future research direction.
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