体外冲击波与自体睾丸鞘膜移植术治疗阴茎硬结症的效果比较

Abstract
Figure/Table
References (18)
Related Citation (2)

Download: PDF (912 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To compare and analyze the clinical efficacy of extracorporeal shockwave and autologous perididymal patch grafting for Peyronie′s disease. Methods From June 2010 to January 2016, in Xuzhou Central Hospital, l20 patients with Peyronie′s disease were selected, according to the random number method, they were divided into control group and observation group, with 10 cases in each group. The control group was treated with extracorporeal shock wave, and the observation group was treated with autologous perididymal patch grafting. The international index of erectile function-5 (IIEF-5), penile curvature between the two groups before and after treatment were compared and analyzed. Results The IIEF-5 score, induration size and penile curvature before and after treatment in control group were compared, the differences were not statistically significant (P > 0.05). After treatment, in the observation group, the IIEF-5 score was significantly higher than that before the treatment, the difference was statistically significant (P < 0.05); penile induration was no recurrence after treatment, the size of penile induration before and after treatment was compared, and the difference was statistically significant (P < 0.05); the penile curvature after treatment was lower than that before treatment, the difference was statistically significant (P < 0.05). The IIEF-5 score, induration size and penile curvature in the two groups after treatment were compared, the differences were statistically significant (P < 0.05). Conclusion The efficacy of extracorporeal shock wave therapy for penile induration is still doubtful. Autologous perididymal patch grafting is a safe and effective surgical method for the treatment of Peyronie′s disease.

Key words： Peyronie′s disease Extracorporeal shockwave Autologous perididymal patch grafting

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHU Guangyuan1* ZHANG Zhiguo2* ZHANG Wenda2 HAN Conghui1
	2▲

Cite this article:

ZHU Guangyuan1* ZHANG Zhiguo2* ZHANG Wenda2 HAN Conghui1,2▲. Comparison of efficacy of extracorporeal shockwave and autologous perididymal patch grafting for Peyronie′s disease[J]. 中国医药导报, 2018, 15(31): 80-82,110.

URL:

http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I31/80

[1] Paulis G，Romano G，Paulis A. Prevalence，psychological impact，and risk factors of erectile dysfunction in patients with Peyronie′s disease: a analysis of 309 cases [J]. Res Rep Urol，2016，8：95-103.retrospective
[2] Dibenedetti DB，Nguyen D，Zografos L，et al. A Population-Based Study of Peyronie′s Disease：Prevalence and Treatment Patterns in the United States [J]. Adv Urol，2011， 2011：282503.
[3] Dolmans GH，Werker PM，De Jong IJ，et al. WNT2 locus is involved in genetic susceptibility of Peyronie′s disease [J]. J Sex Med，2012，9（5）：1430-1434.
[4] Paulis G，Brancato T. Inflammatory mechanisms and oxidative stress in Peyronie′s disease：therapeutic "rationale" and related emerging treatment strategies [J]. Inflamm Allergy Drug Targets，2012，11（1）：48-57.
[5] 朱秀波，姜睿.阴茎硬结症研究进展[J].中华男科学杂志，2013，19（4）：355-359.
[6] Poulakis V，Skriapas K，De Vries R，et al. Extracorporeal shockwave therapy for Peyronie′s disease：an alternative treatment? [J]. Asian J Androl，2006，8（3）：361-366.
[7] Levine LA，Larsen SM. Surgery for Peyronie′s disease[J]. Asian J Androl，2013，15（1）：27-34.
[8] 林浩成，张海涛，姜辉.溶组织羧菌胶原酶治疗阴茎硬结症：一种新的微创有效的治疗方法[J].中华男科学杂志，2017，23（9）：771-775.
[9] Gao L，Qian S，Tang Z，et al. A meta-analysis of extracorporeal shock wave therapy for Peyronie′s disease [J]. Int J Impot Res，2016，28（5）：161-166.
[10] Zaid UB，Alwaal A，Zhang X，et al. Surgical management of Peyronie′s disease[J]. Curr Urol Rep，2014，15（10）：446.
[11] 钟光俊，潘晖，呙林杰，等.斑块切除加对侧白膜折叠术治疗阴茎硬结症[J].长江大学学报：自科版，2016，13（30）：28-29.
[12] Hamed HA，Roaiah M，Hassanin AM，et al. A new technique，combined plication-incision （CPI），for correction of penile curvature [J]. Int Braz J Urol，2018，44（1）：180-187.
[13] Hatzichristodoulou G. Grafting techniques for Peyronie′s disease [J]. Transl Androl Urol，2016，5（3）：334-341.
[14] Hatzichristodoulou G. The PICS Technique：a novel approach for residual curvature correction during penile prosthesis implantation in patients with severe peyronie′s disease using the collagen fleece tachosil [J]. J Sex Med，2018，15（3）：416-421.
[15] Kotov SV，Yusufov AG，Semenov MK. Buccal mucosa transplant the concept of ideal graft in surgical management of peyronies disease [J]. Urologiia，2017，（4）：68-72.
[16] 李志刚，臧光辉，郝林，等.斑块切除加自体睾丸鞘膜移植术治疗阴茎硬结症[J].中华男科学杂志，2018，24（1）：55-58.
[17] 冯宁翰，许斌，杨杰，等.睾丸鞘膜移植治疗阴茎 Peyronies病（附4例报告）[J].中国男科学杂志，2011，25（9）：48-50.
[18] 王亚民，宋乐彬，张嘉宜，等.自体睾丸鞘膜移植治疗阴茎硬结症[J].中华男科学杂志，2016，22（7）：617-620.