|
|
Research progress on intravenous lidocaine in general anesthesia of colorectal cancer patients |
WU Yumin1 YAN Wenjun2 QU Song1 ZHANG Wenjie1 |
1.The First Clinical Medical College, Gansu University of Chinese Medicine, Gansu Province, Lanzhou 730000, China;
2.Department of Anesthesiology, Gansu Provincial Hospital, Gansu Province, Lanzhou 730000, China
|
|
|
Abstract Lidocaine, an amide based local anesthetic, has been widely recognized for its clinical effects during the perioperative period, whether used as a regional anesthetic or as an auxiliary drug for general anesthesia. Lidocaine intravenous injection has the effects of analgesia, sedation, anti-infection, organ protection, promoting gastrointestinal function recovery and inhibiting tumor cell recurrence and metastasis. Colorectal cancer patients are more common in middle-aged and elderly people, and due to factors such as decreased appetite and tumor bleeding in the early stages, patients may experience weight loss, anemia, and poor tolerance to surgery and anesthesia. This review elucidates the advantages of intravenous infusion of lidocaine in general anesthesia for colorectal cancer patients, aiming to optimize perioperative management and improve prognosis.
|
|
|
|
|
[1] Sung H,Ferlay J,Siegel RL,et al. Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J]. CA Cancer J Clin,2021,71(3):209-249.
[2] Talaat IM,Elemam NM,Saber-Ayad M. Complement system:an immunotherapy target in colorectal cancer [J]. Front Immunol,2022,13:810993.
[3] 高宏燕,谭晶.丙泊酚注射痛的发生机制及其预防药物的研究进展[J].中国医药,2022,17(2):312-315.
[4] Beaussier M,Delbos A,Maurice-Szamburski A,et al. Perioperative use of intravenous lidocaine [J]. Drugs,2018,78(12):1229-1246.
[5] Tian S,Zhang D,Zhou W,et al. Median effective dose of lidocaine for the prevention of pain caused by the injection of propofol formulated with medium-and long-chain triglycerides based on lean body weight [J]. Pain Med,2021,22(6):1246-1252.
[6] Hamada K,Takahashi K,Tokinaga Y,et al. Generic rocuronium reduces withdrawal movements compared to original rocuronium under target-controlled infusion induction with propofol [J]. J Anesth,2021,35(2):184-188.
[7] An X,Li C,Sahebally Z,et al. Pretreatment with oxycodone simultaneously reduces etomidate-induced myoclonus and rocuronium-induced withdrawal movements during rapid- sequence induction [J]. Med Sci Monit,2017,23:4989-4994.
[8] 王佳,陈剑锋,崔宇,等.静脉注射利多卡因预防罗库溴铵注射痛/缩肢反应的Meta分析[J].中国循证医学杂志,2020,20(1):79-86.
[9] 王运洁,黄胜.静脉输注利多卡因对腹腔镜下直肠癌根治术后患者镇痛效果的影响[J].吉林医学,2019,40(7):1458-1460.
[10] 朱成成,陆智杰.静脉丙泊酚复合利多卡因镇静在ERCP取石术中的应用[J].南昌大学学报(医学版),2020, 60(5):61-63.
[11] 郭慧,刘香君,刘功俭.利多卡因在无痛结肠镜检查中的效果观察[J].徐州医科大学学报,2020,40(6):458-461.
[12] 赵馨,高洁,张艳丽,等.静脉输注利多卡因用于肛肠手术对患者疼痛介质、炎性应激反应及免疫功能的影响[J].河北医药,2020,42(3):416-419.
[13] 孙芳,邱涛,吴云,等.利多卡因对老年胃癌根治术患者的脑保护作用研究[J].西南国防医药,2019,29(2):173- 175.
[14] Lee EH,Lee HM,Chung CH,et al. Impact of intravenous lidocaine on myocardial injury after off-pump coronary artery surgery [J]. Br J Anaesth,2011,106(4):487-493.
[15] Kim HJ,Kim WH,Kim G,et al. A comparison among infusion of lidocaine and dexmedetomidine alone and in combination in subjects undergoing coronary artery bypass graft:a randomized trial [J]. Contemp Clin Trials,2014,39(2):303-309.
[16] 王磊,孙静,张学广,等.利多卡因对胸腔镜下行肺癌根治术的患者术后恢复质量及肺保护作用的影响[J].医学研究杂志,2021,50(4):119-123.
[17] 袁林芳,赵文静,刘月,等.围术期静脉滴注利多卡因对食管癌患者的肺保护作用研究[J].中国全科医学,2019,22(36):4465-4470.
[18] Tikuisis R,Miliauskas P,Samalavicius NE,et al. Intravenous lidocaine for post-operative pain relief after hand-assisted laparoscopic colon surgery:a randomized,placebo-controlled clinical trial [J]. Tech Coloproctol,2014, 18(4):373-380.
[19] Huang Y,Bo Y,Li Y,et al. The impact of tubeless anesthesia versus intubated anesthesia on cerebral oxygen saturation and postoperative cognitive function in patients undergoing video-assisted thoracoscopic surgery:a randomized trial [J]. J Thorac Dis,2022,14(10):4012-4030.
[20] 赵馨,高洁,张艳丽,等.静脉输注利多卡因用于肛肠手术对患者血流动力学、氧化应激及认知功能的影响[J].河北医药,2020,42(5):754-757.
[21] 薛红,彭贞丹,解成兰.利多卡因对老年胸科手术患者术后早期认知功能障碍的影响[J].山东医药,2017,57(6):75-77.
[22] Kim J,Lee HK. Potential role of the gut microbiome in colorectal cancer progression [J]. Front Immunol,2022,12:807648.
[23] Tat T,Jurj A,Selicean C,et al. Antiproliferative effects of propofol and lidocaine on the colon adenocarcinoma microenvironment [J]. J BUON,2019,24(1):106-115.
[24] Qu X,Yang L,Shi Q,et al. Lidocaine inhibits proliferation and induces apoptosis in colorectal cancer cells by upregulating mir-520a-3p and targeting EGFR [J]. Pathol Res Pract,2018,214(12):1974-1979.
[25] Du J,Zhang L,Ma H,et al. Lidocaine suppresses cell proliferation and aerobic glycolysis by regulating circHOMER1/ miR-138-5p/HEY1 axis in colorectal cancer [J]. Cancer Manag Res,2020,12:5009-5022.
[26] Zi H,Chen L,Ruan Q. Lidocaine represses the malignant behavior of lung carcinoma cells via the circPDZD8/ miR- 516b-5p/GOLT1A axis[J]. Histol Histopathol,2022,37(5): 461-474.
[27] Wang H,Zhang X,Li Y,et al. Lidocaine hampers colorectal cancer process via circITFG2/miR-1204/SOCS2 axis [J]. Anticancer Drugs,2022,33(3):235-244.
[28] Greenwood E,Nimmo S,Paterson H,et al. Intravenous lidocaine infusion as a component of multimodal analgesia for colorectal surgery-measurement of plasma levels [J]. Perioper Med(Lond),2019,8:1.
[29] Carabalona JF,Delwarde B,Duclos A,et al. Serum Concentrations of lidocaine during bariatric surgery [J]. Anesth Analg,2020,130(1):e5-e8.
[30] Kim DH,Park JY,Yu J,et al. Intravenous lidocaine for the prevention of postoperative catheter-related bladder discomfort in male patients undergoing transurethral resection of bladder tumors:a randomized,double-blind,controlled trial [J]. Anesth Analg,2020,131(1):220-227.
[31] Herzog J,Schou M,Jensen KM,et al. A randomised controlled trial of lidocaine infusion on post-operative opioid consumption in patients undergoing robotic colorectal surgery [J]. Dan Med J,2020,67(1):A06190342.
[32] Liu J,Liu X,Peng LP,et al. Efficacy and safety of intravenous lidocaine in propofol-based sedation for ERCP procedures:a prospective,randomized,double-blinded,controlled trial [J]. Gastrointest Endosc,2020,92(2):293-300.
[33] De Oliveira CMB,Coelho LMG,Valad?觔o JA,et al. Assessment of the effect of perioperative venous lidocaine on the intensity of pain and IL-6 concentration after laparoscopic gastroplasty [J]. Obes Surg,2020,30(10):3912-3918.
[34] Ho MLJ,Kerr SJ,Stevens J. Intravenous lidocaine infusions for 48 hours in open colorectal surgery:a prospective,randomized,double-blinded,placebo-controlled trial [J]. Korean J Anesthesiol,2018,71(1):57-65.
[35] Foo I,Macfarlane AJR,Srivastava D,et al. The use of intravenous lidocaine for postoperative pain and recovery:international consensus statement on efficacy and safety [J]. Anaesthesia,2021,76(2):238-250. |
|
|
|