|
|
|
| Summary of Professor Zhao Haibin’s experience of treating double heart disease in the later stage based on classical prescriptions from Shaoyin’s “original meridian self-disease” |
| LIU Yunlin1 ZHAO Haibin2 WANG Chao2 HOU Jiqiu2 LI Ruiyi1 YAN Shasha2 |
1.The Second Clinical Medical College, Beijing University of Chinese Medicine, Beijing 100078, China;
2.Department of Cardiology, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China
|
|
|
|
Abstract Modern medicine regards cardiovascular disease combined with mental and psychological problems as double heart disease. Professor Zhao Haibin, the founder of the “double heart theory” of traditional Chinese medicine, finds that the late stage of double heart disease often leads to the same result and involves the two viscera of the heart and kidney, especially in the elderly, who are often accompanied by depression, deficiency of both heart and kidney yang qi in the later stage of heart disease. Therefore, this paper concludes that the pathogenesis of the late stage of double-heart disease belongs to the “stagnation” stage of “stasis and heat deficiency and stagnation”, that is, the damage of the heart and kidney Yang, the loss of the mind, the yang qi of upper jiao is insufficient, yin qi lower jiao is sufficient and the stagnation of the heart and qi.The treatment should be based on the prescription of the meridian, using syndrome differentiation of six channels theory and eight principles of Shaoyin meridian, the syndrome differentiation of zang-fu viscera and the two viscera of the heart and kidney, the combination of disease and syndrome, considering a syndrome by several diseases, diagnosis and treatment based on syndrome differentiation. The method should warm the heart and kidney, nourishing the heart and calming the mind, promoting blood and activating qi. Sini Decoction combined with self-designed “Shuangxin Decoction” addition and subtraction, the clinical effect proved remarkable.
|
|
|
|
|
|
[1] 陈晓虎，朱贤慧，陈建东，等.双心疾病中西医结合诊治专家共识[J].中国全科医学，2017，20（14）：1659-1662.
[2] 中国中西医结合学会心血管病专业委员会双心学组.双心疾病中西医结合诊治专家共识[J].临床医学研究与实践，2017，2（11）：201.
[3] Jha MK，Qamar A，Vaduganathan M，et al. Screening and Management of Depression in Patients With Cardiovascular Disease： JACC State-of-the-Art Review [J]. J Am Coll Cardiol，2019，73（14）：1827-1845.
[4] 李令康，谷松.《伤寒论》六经辨证论治“双心疾病”[J].中华中医药学刊，2020，38（6）：46-49.
[5] 王昀，王超，丁婉丽，等.双心疾病之冠心病伴焦虑抑郁“瘀热虚滞”病机探析[J].北京中医药大学学报，2022，45（4）：347-352.
[6] 李令康.基于《伤寒杂病论》相关方证的双心疾病辨证论治规律研究[D].沈阳：辽宁中医药大学，2020.
[7] 郭甜甜，林以，李聪，等.肖长江从肝脾肾论治微血管性心绞痛经验[J].湖南中医杂志，2021，37（4）：17-20.
[8] 江泳，江瑞云，陈建杉.论肾阳虚与抑郁症发病的关联性[J].四川中医，2009，27（8）：30-31.
[9] Wang N，Zhu P，Huang R，et al. PINK1：The guard of mitochondria [J]. Life Sci，2020，259：118247.
[10] 齐敏瑞，陈娜，谭从娥.肾阳虚证与线粒体能量代谢功能失调的相关性研究[J].辽宁中医杂志，2018，45（12）：2531-2533.
[11] 李文慧，李阳，于姚，等.基于线粒体能量代谢障碍探讨从脾论治抑郁症的机理[J].环球中医药，2020，13（9）：1494-1498.
[12] 冯世纶.六经八纲读懂伤寒论[M].北京：中国中医药出版社，2014.
[13] 胡希恕.胡希恕伤寒论讲座[M].北京：学苑出版社，2017.
[14] Pope BS，Wood SK. Advances in understanding mechanisms and therapeutic targets to treat comorbid depression and cardiovascular disease [J]. Neurosci Biobehav Rev，2020， 116：337-349.
[15] Sreejit G，Nooti SK，Athmanathan B，et al. S100A8/A9 in Myocardial Infarction [J]. Methods Mol Biol，2019，1929：739-754.
[16] Gao L，Dong Q，Song Z，et al. NLRP3 inflammasome：a pro- mising target in ischemic stroke [J]. Inflamm Res，2017，66（1）：17-24.
[17] 刘朋，滕晶.从“经气运行”角度解析四逆汤治疗寒郁性“思”志病[J].时珍国医国药，2022，33（6）：1403-1405.
[18] 周丽萍，章宸一瑜，戴黎颖，等.张简斋从心肾治疗情志病探析[J].中华中医药杂志，2020，35（2）：967-969.
[19] 张佩文，王键，刘兰林，等.基于临床医案分析新安六大医家温补学术思想及辨治特色[J].中国中医基础医学杂志，2020，26（4）：451-454.
[20] 王付.学用四逆汤方证的思考与探索[J].中华中医药杂志，2017，32（2）：635-637.
[21] 王多德，席孝萍，刘吉宗，等.当归四逆汤治疗阴寒凝滞型冠心病不稳定性心绞痛疗效观察[J].西部中医药，2021，34（5）：120-121.
[22] Wang C, Hou J, Du H，et al. Anti-depressive effect of Shu- angxinfang on rats with acute myocardial infarction： Promoting bone marrow mesenchymal stem cells mobilization and alleviating inflammatory response [J]. Biomed Pharmacother，2019，111：19-30.
[23] 侯季秋，史金玉，安莹，等.双心方治疗冠心病心绞痛合并抑郁状态临床观察[J].河南中医，2019，39（2）：224- 227.
[24] 黄乐曦，杜泓森，靳会会，等.双心方治疗心肌梗死后抑郁的网络药理学研究[J].中医学报，2021，36（9）：1985- 1991.
[25] 刘祥，唐卓然，齐鑫，等.基于数据挖掘分析赵海滨教授治疗双心疾病的组方规律及用药经验[J].中国医药导报，2022，19（6）：29-33.
[26] Sun Y，Wang Z，Hou J，et al. Shuangxinfang Prevents S100 A9-Induced Macrophage/Microglial Inflammation to Improve Cardiac Function and Depression-Like Behavior in Rats After Acute Myocardial Infarction [J]. Front Pharmacol，2022，13：832590. |
|
|
|
