Abstract Objective To explore the clinical value of glycosylated hemoglobin (HbA1c) in type 2 diabetes mellitus (T2DM) complicated with post-stroke pneumonia. Methods A total of 120 patients with T2DM complicated with post-stroke pneumonia admitted to Rugao People’s Hospital (hereinafter referred to as “our hospital”) of Jiangsu Province from December 2019 to December 2021 were selected as the study group, and 112 patients with T2DM complicated with stroke and no pneumonia admitted to our hospital during the same period were selected as the control group. The clinical features of the two groups were compared, and the factors affecting the incidence of T2DM complicated with post-stroke pneumonia were analyzed, the value of serum HbA1c level in predicting the incidence of T2DM complicated with post-stroke pneumonia was further analyzed by receiver operating characteristic (ROC) curve. Results There were significant differences in the proportion of consciousness disorder, National Institutes of Health stroke scale score, C-reactive protein, procalcitonin, fasting blood glucose, white blood cell count, and HbA1c level between the study group and the control group (P＜0.05). The results of multivariate analysis showed that HbA1c level (OR=3.177, 95%CI: 1.143-8.828) and disorder of consciousness (OR=2.971, 95%CI: 1.587-5.564) were independent factors for the occurrence of T2DM complicated with post-stroke pneumonia (P＜0.05). ROC curve results showed that the cut-off value was 7.83%, sensitivity was 84.17%, specificity was 95.54%, and area under the curve was 0.930 for serum HbA1c level to predict T2DM complicated with post-stroke pneumonia (P＜0.05). Conclusion Serum HbA1c level is abnormally elevated in patients with T2DM complicated with post-stroke pneumonia, and HbA1c level is an independent influencing factor of T2DM complicated post-stroke pneumonia. Dynamic monitoring of Hba1c level is of great value in predicting the occurrence of T2DM complicated with post-stroke pneumonia.
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