加味苍附导痰汤治疗痰湿型单纯性肥胖症伴血脂异常的临床效果

doi:10.20047/j.issn1673-7210.2023.12.34

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Abstract Objective To survey the clinical effect of Cangfu Daotan Decoction on the treatment of simple obesity with dyslipidemia of phlegm dampness type complicated with dyslipidemia. Methods A total of 72 cases of simple obesity with dyslipidemia of phlegm dampness type were selected from the outpatients or inpatients of Department of Endocrinology of Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from September 2018 to January 2020. They were divided into control group and treatment group according to random number table method, with 36 cases in each group. The control group were treated with basic treatment and Metformin, the treatment group were treated with Cangfu Daotan Decoction based on the control group. Both groups were treated for 12 weeks. Body mass index (BMI), abdominal circumference, insulin resistance index (HOMA-IR), blood lipid, traditional Chinese medicine syndrome score and clinical efficacy of the two groups before and after treatment were observed. After treatment, BMI, abdominal circumference, HOMA-IR, blood lipid and traditional Chinese medicine syndrome score in both groups were lower than those before treatment, and the treatment group was lower than the control group (P＜0.05). After treatment, total cholesterol, triglycerides, and low density lipoprotein cholesterol in both groups were decreased than those before treatment (P＜0.05), but there was no significant difference between the two groups (P＞0.05). The clinical effect of the treatment group was better than that of the control group (P＜0.05). Conclusion Cangfu Daotan Decoction can reduce the abdominal and waist circumference of simple obesity with dyslipidemia of phlegm dampness type, effectively improve the lipid metabolism and insulin resistance, and improve the clinical symptoms of the patients.

Key words： Obesity Phlegm dampness type Dyslipidemia Cangfu Daotan Decoction

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	YANG Xinyu1 YANG Hua1 TANG Hong1 FENG Shengyu2 MA Yanyun1 ZOU Ran3 PAN Keyi1 JI Benwei1

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YANG Xinyu1 YANG Hua1 TANG Hong1 FENG Shengyu2 MA Yanyun1 ZOU Ran3 PAN Keyi1 JI Benwei1. Clinical effect observation of Cangfu Daotan Decoction on the treatment of simple obesity with dyslipidemia of phlegm dampness type complicated with dyslipidemia[J]. 中国医药导报, 2023, 20(12): 151-155.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.12.34 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I12/151

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