磁振磁电疗法治疗湿热瘀阻型慢性前列腺炎/慢性盆底疼痛综合征的效果及对单核细胞趋化蛋白-1、血管细胞黏附因子-1的影响

doi:10.20047/j.issn1673-7210.2023.12.21

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Abstract Objective To observe the effect of magnetic resonance electromagnetic therapy on chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) with damp-heat and blood-stasis and its effect on monocyte chemotactic protein-1 (MCP-1) and vascular cell adhesion molecule (VCAM-1). Methods A total of 110 CP/CPPS patients with damp-heat and blood-stasis treated in Guangdong Provincial Hospital of Chinese Medicine Zhuhai Hospital from January 2021 to January 2022 were selected. They were divided into experimental group and control group by random number table method, with 55 cases in each group. The control group was treated with Qianliebeixi Capsules and the experimental group was treated with magnetic resonance electromagnetic therapy, and the for two courses. National Institutes of Health chronic prostatic inflammation (NIH-CPSI), clinical efficacy, traditional Chinese medicine syndrome score, traditional Chinese medicine syndrome efficacy, prostatic fluid level of VCAM-1, MCP-1, and incidence of adverse reactions were compared between two groups. Results After treatment, the scores of NIH-CPSI and traditional Chinese medicine syndrome of two groups were lower than those before treatment, and experimental group was lower than control group (P＜0.05). The clinical efficacy of experimental group was better than that of control group (P＜0.05). The traditional Chinese medicine syndrome efficacy of experimental group was better than that of control group (P＜0.05). After treatment, the levels of MCP-1 and VCAM-1 in two groups were lower than those before treatment, and experimental group was lower than control group (P＜0.05). No adverse reactions such as local pain, rubefaction, blister, and general discomfort were observed in both groups. Conclusion Magnetic resonance electromagnetic therapy has a good effect in treating CP/CPPS with damp-heat and blood-stasis, and its mechanism may be related to regulating MCP-1 and VCAM-1 levels, stimulating immune function and inhibiting inflammation.

Key words： Chronic prostatitis/chronic pelvic pain syndrome Damp-heat and blood-stasis Monocyte chemotactic protein-1 Vascular cell adhesion molecule-1 Magnetic resonance electromagnetic therapy

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	LIANG Yichun1 WANG Wen1 YUAN Shaoying2

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LIANG Yichun1 WANG Wen1 YUAN Shaoying2. Effect of magnetic resonance electromagnetic therapy on chronic prostatitis/chronic pelvic pain syndrome with dampness-heat and blood-stasis and its effect on monocyte chemotactic protein-1 and vascular cell adhesion molecule-1[J]. 中国医药导报, 2023, 20(12): 94-97,102.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.12.21 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I12/94

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