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Research advances in the study of serological markers of cholestasis |
CAO Xuemei ZHANG Shujun |
Department of Infectious Diseases, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
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Abstract The diagnosis of cholestasis is currently facing a major challenge, and the development of new markers has become a hot topic of cholestasis-related research in recent years. Newly discovered serological markers in recent years, including transferrin, high mobility group protein B1, myeloid cell trigger receptors, chitin Plasma-3-like protein-1, cytokeratin, microRNA, long non-coding RNA, circular RNA, lamin B receptor antibody, and anti-Kelch-like 12 protein antibody, IgM, etc. in the diagnosis and prognosis of cholestasis have been summarized in the present manuscript, that are classified into inflammation-related markers, non-coding RNAs, and immunological indicators. The results and value of the research were analyzed and summarized, in order to provide reference for follow-up research.
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