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Research progress on the relationship between trimethylamine-N-oxide and chronic kidney disease and its complications
YANG Xiangyan1   TIAN Maolu2   ZHA Yan1
1.Graduate School, Zunyi Medical University, Guizhou Province, Zunyi   563000, China; 
2.Department of Nephrology, Guizhou Provincial People’s Hospital, Guizhou Province, Guiyang   550002, China
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Abstract  With the deepening of the research on the “gut-kidney axis”, the relationship between trimethylamine-N-oxide, the metabolic compound of intestinal flora, and chronic kidney disease has become a research hotspot for scholars at home and abroad, providing a new target for the prevention and treatment of chronic kidney disease. This paper reviews the relationship between trimethylamine-N-oxide and chronic kidney disease in recent years, and the promotion of cardiovascular disease, cognitive impairment, peritonitis, cerebrovascular disease, and other complications through inducing oxidative stress and inflammatory response, in order to provide reference ideas for the clinical prevention and treatment of chronic kidney disease and its related complications.
Key wordsTrimethylamine-N-oxide      Chronic kidney disease      Complications      Research progress     
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YANG Xiangyan1 TIAN Maolu2 ZHA Yan1
Cite this article:   
YANG Xiangyan1 TIAN Maolu2 ZHA Yan1. Research progress on the relationship between trimethylamine-N-oxide and chronic kidney disease and its complications[J]. 中国医药导报, 2023, 20(11): 57-60.
URL:  
https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.11.13     OR     https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I11/57
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