18F-FDG PET/CT在肺部磨玻璃结节良恶性鉴别诊断中的应用价值

doi:10.20047/j.issn1673-7210.2023.10.30

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Abstract Objective To explore the application value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in the differrentiation of benign and malignant pulmonary ground glass nodules (GGN). Methods Sixty patients (63 GGN [diameter ≥5 mm]) with complete 18F-FDG PET/CT image data and pathologically confirmed by surgery or puncture biopsy were selected from Chongqing Huajianyoufang Hospital from February 2016 to April 2021. The morphological manifestations of the lesions were analyzed, and maximum standard uptake value (SUVmax) of lesions were calculated. Results Among the 63 GGN, 38 were mixed GGN (7 benign and 31 malignant), and 25 were pure GGN (12 benign and 13 malignant). There were 40 adenocarcinoma, 2 squamous cell carcinoma, and 2 adenosquamous cell carcinoma in malignant GGN. There were 12 inflammation, 6 tuberculosis, and 1 atypical hyperplasia of alveolar epithelium in benign GGN. There were significant differences in the size, margin, and density of benign and malignant GGN lesions (P＜0.05); there was no significant difference in GGN location between benign and malignant (P＞0.05). SUVmax≥1.0 in benign and malignant mGGN was statistically significant (P＜0.05); there was no statistical significance in SUVmax≥1.0 between benign and malignant pGGN (P＞0.05). Conclusion 18F-FDG PET/CT can provide imaging and metabolic information in the differential diagnosis of benign and malignant pulmonary GGN, which has important clinical value.

Key words： Fluorodeoxyglucose Positron emission tomography/computed tomography Pulmonary ground glass nodules Differential diagnosis

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	LI Zhong1 JI Yong2 WANG Jiao1 LI Qi3 CHEN Yu1 FU Shangzhi4 XIE Xiangxian2 AO Qiuhong1 WANG Zhenhui1 WEN Ming3

Cite this article:

LI Zhong1 JI Yong2 WANG Jiao1 LI Qi3 CHEN Yu1 FU Shangzhi4 XIE Xiangxian2 AO Qiuhong1 WANG Zhenhui1 WEN Ming3. Application value of 18F-FDG PET/CT in differential diagnosis of benign and malignant pulmonary ground glass nodules[J]. 中国医药导报, 2023, 20(10): 134-137.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.10.30 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I10/134

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