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Data mining of acupoint spectrum and stimulation parameters in electro-acupuncture treatment of knee osteoarthritis |
LI Yuexin1 LIU Di2 FANG Zhiyuan3 LI Hua2 CUI Yujie1 LI Yuan1 |
1.The Second Clinical Medical College, Beijing University of Chinese Medicine, Beijing 100078, China;
2.Department of Acupuncture and Moxibustion, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China;
3.Department of Orthopedics, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China
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Abstract Objective To study the acupoint spectrum and common stimulation parameters of electro-acupuncture treatment of knee osteoarthritis. Methods Clinical literatures on electro-acupuncture treatment of knee osteoarthritis collected from China National Knowledge Infrastructure, Wanfang Data, and PubMed from inception to December 2021 were searched to establish a database of electro-acupuncture point selection and stimulation parameters for knee osteoarthritis. Descriptive statistics, cluster analysis, and association rule analysis were conducted on the data. Results According to the analysis of 51 prescriptions in 51 literatures included, the acupoints with high frequency of use were successively dúbí, nèixīyǎn, xuèhǎi, liángqiū, and ashi point. The main acupoints meridians were the stomach meridian of foot-yangming, extra ordinary point, and spleen meridian of foot-taiyin. The two most commonly connected acupoint pairs of electro-acupuncture were nèixīyǎn-dúbí and liángqiū-xuèhǎi. Cluster analysis results in eight cluster clusters. The highest degree of support in association rules was the combination of dúbí and nèixīyǎn. The most commonly used stimulation parameters were: rarefaction wave, dilatational wave, 2 Hz, 2/100 Hz, intensity tolerance, 30 min/time, once every other day, and total treatment time of four weeks. Conclusion Electro-acupuncture treatment of knee osteoarthritis is mainly based on local acupoint selection, supplemented by syndrome differentiation along channel, and combined treatment of muscles and bones. Attention should be paid to the selection of electro-acupuncture points and waveforms. The treatment interval should not be too long, and the retention time of needles can be extended appropriately within the safe range, so as to provide reference for clinical use of acupoint and stimulation parameter selection of electro-acupuncture in the treatment of knee osteoarthritis.
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