基于聚类-因子分析的缺血性中风恢复期肾虚证证候特征研究

doi:10.20047/j.issn1673-7210.2023.09.02

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Abstract Objective To analyze the syndrome characteristics and rules of kidney deficiency syndrome in patients with ischemic stroke convalescence. Methods Based on previous preparation the four diagnostic information collection form of traditional Chinese medicine for kidney deficiency syndrome during ischemic stroke convalescence, a prospective multi-center survey was conducted to collect clinical information in 15 sub-centers including Dongzhimen Hospital, Beijing University of Chinese Medicine from February 2018 to June 2019, and cluster analysis and factor analysis were used to conduct data mining on syndrome characteristics and distribution rules. Results A total of 970 cases of four diagnosis information collection, a total of 33 items of four diagnostic information were analyzed, among which seven items with frequency ≥50% were slow movement, soreness of waist, forgetfulness, weakness of knee, frequent nocturnal urination, soreness of knee, and weakness of waist, respectively. Based on the systematic cluster analysis and expert opinions, it was found that the information dispersion of cluster three categories (kidney qi [essence] deficiency, kidney yang deficiency, kidney yin deficiency) was the best, and the characteristic dimensions of the three categories of clinical symptoms were extracted through factor analysis, and presented in two dimensions of function and form. Conclusion Through cluster-factor analysis, the clinical symptom and dimension characteristics of kidney deficiency syndrome during ischemic stroke convalesce period are initially revealed, and the relevant diagnostic scale is further constructed to provide basis.

Key words： Ischemic stroke convalesce Kidney deficiency syndrome Cluster analysis Factor analysis Syndrome characteristics

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	DONG Xinglu1 GAO Ying1 TANG Lu1 GUO Shengnan2 LIU Qiang3 ZHOU Li1

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DONG Xinglu1 GAO Ying1 TANG Lu1 GUO Shengnan2 LIU Qiang3 ZHOU Li1. Study on syndrome characteristics of kidney deficiency syndrome during ischemic stroke convalescence based on cluster-factor analysis[J]. 中国医药导报, 2023, 20(9): 12-16.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.09.02 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I9/12

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